ArticleJournal of attention disorders2024
Childhood Clinical Features Preceding the Onset of Bipolar Versus Major Depressive Disorders During Adolescence.
Article in Journal of attention disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Sex differences in pediatric major depressive episodes: a cross-sectional study on psychiatric symptoms in early-onset mood disorders.Frontiers in psychiatry · 2025Article
- Depression severity and verbal comprehension in children and adolescents with a major depressive episode.Frontiers in psychiatry · 2024Article
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Authors and funding
9 authors.
Funding
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Abstract
objectiveTo identify childhood psychopathological features that predict the onset of adolescent Bipolar (BD) versus Unipolar Major Depressive Disorder (UD) during adolescence.
methodWe analyzed clinical data from 495 juveniles diagnosed with DSM-5 UD (
resultsBD subjects exhibited earlier onset of any psychiatric feature compared to UD. Antecedents associated with later BD were: oppositional defiant > specific phobias > ADHD > obsessive compulsive (OCD). Antecedents selectively associated with later UD were: social anxiety and separation anxiety. Factors significantly and independently associated with later BD diagnosis were: [a] emotional dysregulation at onset of the mood disorder; [b] first depressive episode with mixed features; [c] antecedent ADHD; [d] antecedent OCD, and [e] antecedent oppositional-defiance.
conclusionIdentifying developmental differences in BD and UD symptoms can aid clinicians in early identification and treatment planning for bipolar disorder in youth.
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