ArticleLipids in health and disease2024
The association between remnant cholesterol and rheumatoid arthritis: insights from a large population study.
Article in Lipids in health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 34 citations in OpenAlex.
- Association of the dietary carbohydrate-to-fiber ratio with prevalent rheumatoid arthritis in NHANES 2009-2018.Medicine · 2026Article
- Remnant cholesterol inflammation index (RCII) as a potential biomarker for ACPA-negative rheumatoid arthritis: evidence from dual-cohort analysis and serum lipidomics.Clinical rheumatology · 2026Article
- Association between remnant cholesterol level and gout in US adults.The Journal of international medical research · 2026Article
- Remnant cholesterol and lipid ratios predict the relapse of neuromyelitis optica spectrum disorder.Lipids in health and disease · 2026Article
- Prevalence and Patterns of Dyslipidemia Among Patients With Rheumatoid Arthritis: A Retrospective Cohort Study.Cureus · 2025Article
- Metabolically healthy obesity increases the risks of MASLD and hyperuricemia: a cohort study with mediation analysis.BMC endocrine disorders · 2025Article
- Risk of remnant cholesterol and chronic obstructive pulmonary disease: a mendelian randomization study.Journal of thoracic disease · 2025Article
- A nutrient wide association study of cardiovascular disease prevalence in older adults from NHANES 2007 to 2018.Scientific reports · 2025Article
- Effects of remnant cholesterol on adverse renal outcomes in lupus nephritis.Lipids in health and disease · 2025Observational
- Association between lipid accumulation products and relative handgrip strength: a large population-based study.Scientific reports · 2025Article
- Association between remnant cholesterol (RC) and endometriosis: a cross-sectional study based on NHANES data.Lipids in health and disease · 2025Article
- Beyond cardiovascular disease: remnant cholesterol as a novel risk factor for osteoarthritis.Frontiers in nutrition · 2025Article
- The Impact of Triglycerides on Rheumatoid Arthritis: Risk Factor and Mendelian Randomization Study.Open access rheumatology : research and reviews · 2025Article
- Association between remnant cholesterol and risk of kidney stones: a case-control study in Chinese adults.Urolithiasis · 2024Article
- Remnant cholesterol elevates hyperuricemia risk in the middle aged and elderly Chinese: a longitudinal study.Scientific reports · 2024Article
- Association of systemic immune-inflammation index with body mass index, waist circumference and prevalence of obesity in US adults.Scientific reports · 2024Article
- Is systemic inflammation a missing link between cardiometabolic index with mortality? Evidence from a large population-based study.Cardiovascular diabetology · 2024Article
- Is erectile dysfunction associated with osteoarthritis and rheumatoid arthritis? Insights from a population-based study.Sexual medicine · 2024Article
- The association between remnant cholesterol and bone mineral density in US adults: the National Health and Nutrition Examination Survey (NHANES) 2013-2018.Lipids in health and disease · 2024Article
- Association between oxidative balance score and rheumatoid arthritis in female: a cross-sectional study.BMC women's health · 2024Observational
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
objectivesWhile lipid metabolism disorder is widely acknowledged as a contributing factor to inflammation, the association between remnant cholesterol (RC), which indicates lipid metabolism, and rheumatoid arthritis (RA) has not been investigated. Accordingly, this study evaluated whether RC is associated with RA disease events.
methodsData were collected and specifically extracted from the National Health and Nutrition Examination Survey (NHANES) 1999-2008 database. The RC value was derived by subtracting the combined amount of low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) from the total cholesterol (TC). The association between RC and RA was evaluated using multivariate regression analysis and subgroup analysis.
resultsThe study analyzed 7777 patients, of which 581 patients (7.47%) were diagnosed with RA. After accounting for different covariates, the multivariate logistic regression analysis revealed a notable correlation between increased RC levels and an increased likelihood of RA (odds ratio OR = 1.54; 95% confidence interval CI: 1.11-2.13; P = 0.0092). The interaction test did not yield statistically significant effects on this association. The linear correlation between RC and RA was observed within restricted cubic spline regression model limitations.
conclusionThe results suggest that higher RC levels are associated with increased odds of RA, indicating that RC can serve as a novel and convenient index for forecasting the likelihood of RA in the United States. Additionally, these findings offer insights into early intervention strategies for susceptible populations at risk of developing RA.
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