olf413 an octopamine biogenesis pathway gene is required for axon growth and pathfinding during embryonic nervous system development in Drosophila melanogaster.

Ravindrakumar Ramya, Chikkate Ramakrishnappa Venkatesh, Baragur Venkatanarayanasetty Shyamala

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Article in BMC research notes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 authors at 1 institution in 1 country.

Ravindrakumar RamyaDevelopmental Genetics Laboratory, Department of Studies in Zoology, University of Mysore, Mysuru, 570006, India.

Chikkate Ramakrishnappa VenkateshDevelopmental Genetics Laboratory, Department of Studies in Zoology, University of Mysore, Mysuru, 570006, India.

Baragur Venkatanarayanasetty ShyamalaDevelopmental Genetics Laboratory, Department of Studies in Zoology, University of Mysore, Mysuru, 570006, India. shyamalabv@yahoo.com.

University of Mysore · IN

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6 · The paper itself

Abstract

objectiveNeurotransmitters have been extensively studied as neural communication molecules. Genetic associations discovered, and indirect intervention studies in Humans and mammals have led to a general proposition that neurotransmitters have a role in structuring of neuronal network during development. olf413 is a Drosophila gene annotated as coding for dopamine beta-monooxygenase enzyme with a predicted function in octopaminergic pathway. The biological function of this gene is very little worked out. In this study we investigate the requirement of olf413 gene function for octopamine biogenesis and developmental patterning of embryonic nervous system.

resultIn our study we have used the newly characterized neuronal specific allele olf413

Indexed as

Drosophila melanogasterDrosophila ProteinsAnimalsAxonsDrosophilaHumansMammalsNeurotransmitter AgentsOctopamineDrosophila ProteinsNeurotransmitter AgentsOctopamineAxonal growthAxonal pathfindingDopamineDrosophilaNervous system developmentOctopamineolf413TβH

Identifiers

PMID38326892

DOI10.1186/s13104-024-06700-3

PMCPMC10848397

OpenAlexW4391604196

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