ArticleBMC sports science, medicine & rehabilitation2024
The effect of high-intensity intermittent and moderate-intensity continuous exercises on neurobiological markers and cognitive performance.
Article in BMC sports science, medicine & rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Repetitive Head Impacts During Contact Sports and Fluid Biomarkers of Neural Damage: A Meta-analysis.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- High-intensity interval training differentially modulates acute BDNF and cognitive responses in young adult males: a randomized crossover trial.Scientific reports · 2026Trial
- Trial
- Effort intensification and restoration in short-term HIIT predict strategic control in complex tasks.Scientific reports · 2025Trial
- Effects of a three-month exercise programme on cognition, mood and neurogenesis: the NeuroFit randomised controlled trial.npj aging · 2026Article
- Cognitive and biochemical responses to continuous moderate and extensive interval exercise in randomized elderly male rats.BMC sports science, medicine & rehabilitation · 2026Article
- Neural Efficiency and Sensorimotor Adaptations in Swimming Athletes: A Systematic Review of Neuroimaging and Cognitive-Behavioral Evidence for Performance and Wellbeing.Brain sciences · 2026Review
- The Effects of Varying Intensities of Unilateral Handgrip Fatigue on Bilateral Movement.Brain sciences · 2025Article
- Targeted exercise interventions on stress, anxiety, depression, and sleep disorders in PhD students.World journal of psychiatry · 2025Article
- Acute Neurochemical, Psychophysiological, and Cognitive Responses to Small-Sided Games vs. Running-Based HIIT in Young, Male Soccer Players.Healthcare (Basel, Switzerland) · 2025Article
- A Single Bout of Physical Exercise Mimicking a Motor Seizure Increases Serum MMP-9, but Not S100B.International journal of molecular sciences · 2025Article
- Mechanisms of the biological response cascade to exercise-induced stress: a comprehensive review.Frontiers in sports and active living · 2025Review
- Correlation between physical activity levels and the risk of cognitive impairment in Chinese older adults.Frontiers in aging neuroscience · 2025Article
- Review
- The Effect of High-Intensity Interval Training (HIIT) on Brain-Derived Neurotrophic Factor Levels (BNDF): A Systematic Review.Brain sciences · 2024Review
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10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe effects of exercise on cognitive functions and general brain health have been increasingly studied. Such studies conducted among athletes are very important to understanding the effects of different exercise methods on biochemical parameters and cognitive performance. The present study aimed to compare the neuroprotective effects of high-intensity interval exercise (HIIE) and moderate-intensity continuous exercise (MICE) based on biochemical parameters and cognitive performance in athletes.
methodsA total of twenty-eight elite male boxing athletes aged > 18 years, with at least eight years of training experience, who successfully achieved national and international levels were included in this study. The elite athletes participating in the study were aged 24.43 ± 4.72 years, 14.45 ± 5.89 years of training experience, had a body weight of 74.64 ± 7.82 kg, and had a height of 177 ± 7.15 cm. Athletes who consumed any stimulants during the testing or supplementation phase, nutritional supplements, or steroids that may have affected hormone levels or sports performance in the last three months were excluded from this study. Venous blood samples were obtained, and cognitive performance tests (Stroop tests) were applied (i) immediately after high-intensity intermittent exercise (HIIE), (ii) one hour after HIIE, (iii) immediately after moderate-intensity continuous exercise (MICE), and (iv) one hour after MICE. Serum BDNF, S100B, and NSE levels were measured after each session.
resultsSerum BDNF levels were significantly (F =
conclusionHIIE and MICE have favorable effects on improving cognitive performance and neuroprotection in an athlete population. HIIE is considered to be superior to MICE in improving neuroprotection and cognitive performance. Our study has remarkable results demonstrating the benefits of HIIT on neuroprotection and cognitive performance. HIIE is recommended instead of MICE, especially in sports where cognitive performance is more important.
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