Evidence map›Paper›PMID 38326710›Full record

ArticleJournal of stroke2024

Adding Tirofiban on Top of Recombinant Tissue Plasminogen Activator May Improve Clinical Outcome in Acute Stroke Patients.

Ruhui Liu, Zhigang Liang, Wei Li, Yan Zhan, Luyao Xu, Shaowan Yang, Guomin Zheng, Li Jiang, Liwen Xie, Zhongwen Sun and 1 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of stroke, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07290751 (Intravenous Thrombolysis Combined With Tirofiban in Acute Ischemic Stroke), which is not on this map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07290751 phase4recruitingnot on this mapstarted 2025, after this paper: background citation

Intravenous Thrombolysis Combined With Tirofiban in Acute Ischemic Stroke: A Multicenter, Prospective, Double-Blind, Placebo-Controlled, Randomized Controlled Trial

TypeinterventionalSponsorBeijing Anzhen HospitalRan2025 to 2026Enrolled976ConditionsAcute Ischemic StrokeArmsTirofiban, Placebo (0.9% normal saline)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ruhui LiuDepartment of Neurology, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai Regional Sub-Center of China National Clinical Research Center for Neurological Diseases, Yantai, China.
Zhigang LiangDepartment of Neurology, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai Regional Sub-Center of China National Clinical Research Center for Neurological Diseases, Yantai, China.
Wei LiDepartment of Neurology, Beijing Tiantan Hospital affiliated to Capital Medical University, Beijing, China.
Yan ZhanThe Second Clinical Medical College, Binzhou Medical University, Yantai, China.
Luyao XuDepartment of Neurology, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai Regional Sub-Center of China National Clinical Research Center for Neurological Diseases, Yantai, China.
Shaowan YangDepartment of Neurology, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai Regional Sub-Center of China National Clinical Research Center for Neurological Diseases, Yantai, China.
Guomin ZhengDepartment of Neurology, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai Regional Sub-Center of China National Clinical Research Center for Neurological Diseases, Yantai, China.
Li JiangDepartment of Neurology, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai Regional Sub-Center of China National Clinical Research Center for Neurological Diseases, Yantai, China.
Liwen XieDepartment of Neurology, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai Regional Sub-Center of China National Clinical Research Center for Neurological Diseases, Yantai, China.
Zhongwen SunDepartment of Neurology, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai Regional Sub-Center of China National Clinical Research Center for Neurological Diseases, Yantai, China.
Yinbao HuDepartment of Neurology, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai Regional Sub-Center of China National Clinical Research Center for Neurological Diseases, Yantai, China.

Funding

Yantai Science and Technology Plan Project 2018SFGY092Yantai Science and Technology Plan Project 2021YD033
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID38326710
PMCPMC10850455

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.