Evidence map›Paper›PMID 38326660›Full record

ArticleTropical animal health and production2024

Genetic diversity of SNPs associated with candidate genes for heat stress in Coreño Creole cattle in Mexico.

César G Luna-Azuara, Moisés Montaño-Bermúdez, René Calderón-Chagoya, Ángel Ríos-Utrera, Guillermo Martínez-Velázquez, Vicente E Vega-Murillo

Abstract read
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In one paragraph

Article in Tropical animal health and production, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

César G Luna-AzuaraFacultad de Medicina Veterinaria y Zootecnia, Universidad Veracruzana, Veracruz, Ver, Mexico.ORCID http://orcid.org/0000-0003-1412-4832
Moisés Montaño-BermúdezCentro Nacional de Investigación Disciplinaria en Fisiología y Mejoramiento Animal INIFAP, Ajuchitlán, Querétaro, Mexico.ORCID http://orcid.org/0000-0003-3162-6949
René Calderón-ChagoyaCentro Nacional de Investigación Disciplinaria en Fisiología y Mejoramiento Animal INIFAP, Ajuchitlán, Querétaro, Mexico.ORCID http://orcid.org/0000-0002-4450-8979
Ángel Ríos-UtreraFacultad de Medicina Veterinaria y Zootecnia, Universidad Veracruzana, Veracruz, Ver, Mexico.ORCID http://orcid.org/0000-0003-3108-1133
Guillermo Martínez-VelázquezCampo Experimental Santiago Ixcuintla-INIFAP, Santiago Ixcuintla, Nayarit, Mexico.ORCID http://orcid.org/0000-0001-6101-1297
Vicente E Vega-MurilloFacultad de Medicina Veterinaria y Zootecnia, Universidad Veracruzana, Veracruz, Ver, Mexico. vvega@uv.mx.ORCID http://orcid.org/0000-0002-0847-8944
Instituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias · MXUniversidad Veracruzana · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mexican Coreño Creole cattle are an important genetic resource adapted to local environmental conditions, so the study of their genetic diversity is essential to know their status and implement conservation programs and their use for crossbreeding. This study evaluated the genetic diversity of heat stress tolerance characteristics of Coreño Creole cattle, and a gene ontology enrichment was performed to know the biological processes in which candidate genes are involved. A total of 48 samples from three localities of Nayarit were genotyped using 777 K Illumina BovineHD BeadChip and 34 single nucleotide polymorphisms associated with candidate genes were selected. Genetic diversity was analyzed using allelic frequencies, expected heterozygosity (He), and Wright's fixation index (FST) using PLINK v1.9 software. Candidate genes were uploaded to the open-source GOnet for pathway analysis and linkage to biological processes. Coreño Creole cattle showed low genetic diversity (He = 0.35), the average FST obtained was 0.044, and only eight markers had allele frequencies higher than 0.80 in the three locations. We found that the genes GOT1 and NCAD are related in the biological processes of stress response, cell differentiation, and homeostatic process. The results revealed that Coreño Creole cattle have low genetic diversity; this could be due to the isolation of these populations.

Indexed as

Heat-Shock ResponsePolymorphism, Single NucleotideAnimalsCattleGene FrequencyGenetic VariationGenotypeMexicoAllelic frequenciesConservationCreole cattleFSTGene ontology

Identifiers

PMID38326660
OpenAlexW4391617756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.