Evidence map›Paper›PMID 38326656›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2024

Preclinical study and first-in-human imaging of [

Lifang Liu, Jiawei Zhong, Ziqi Zhang, Xiaoting Ye, Xinlu Wang, Shaoyu Liu, Zhanwen Zhang

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Head-to-head comparison ofEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Clinical comprehensive evaluation of [European journal of nuclear medicine and molecular imaging · 2025
    Article
  7. Preclinical evaluation of [Scientific reports · 2025
    Article
  8. Design, Synthesis, and Biological Evaluation of a Novel [Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  9. Radiopharmaceuticals and their applications in medicine.Signal transduction and targeted therapy · 2025
    Review
  10. Review
  11. [European journal of nuclear medicine and molecular imaging · 2024
    Article
  12. Article
  13. World journal of gastrointestinal oncology · 2024
    Article
  14. Article
  15. Comparison ofFrontiers in oncology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lifang LiuNuclear Medicine Department, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510120, China.
Jiawei ZhongDepartment of Nuclear Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Ziqi ZhangDepartment of Nuclear Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Xiaoting YeNuclear Medicine Department, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510120, China.
Xinlu Wang *Department of Nuclear Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China. 71lu@163.com.
Shaoyu Liu *Department of Nuclear Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China. shaoyuliu@tju.edu.cn.
Zhanwen Zhang *Nuclear Medicine Department, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510120, China. zhzhanw7@mail.sysu.edu.cn.

Funding

Basic and Applied Basic Research Foundation of Guangdong Province No. 2020A1515110159National Natural Science Foundation of China No.81901772National Natural Science Foundation of China No.82001879Natural Science Foundation of Guangdong Province 2023A1515011300Natural Science Foundation of Guangdong Province No.2019A1515011893Science and Technology Project of Guangzhou City No. 202102010354State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia&The First People's Hospital of Kashi Fund No.SKL-HIDCA-2020-KS2Zhong Nanshan Medical Foundation of Guangdong Province ZNSA-2020003
6 · The paper itself

Abstract

purposeFibroblast-activated protein (FAP) is highly expressed in cancer-associated fibroblasts (CAFs) of many solid cancers, but low or absent in normal tissues. Our study aimed to develop a novel FAP-specific tracer, namely [

methods[

resultsThe radiolabeling yield of [

conclusion[

Indexed as

Fluorodeoxyglucose F18NeoplasmsPositron Emission Tomography Computed TomographyAgedAnimalsCell Line, TumorEndopeptidasesFemaleFibroblast Activation Protein AlphaHEK293 CellsHumansMaleMembrane ProteinsMiceMiddle AgedRadiopharmaceuticalsEndopeptidasesFibroblast Activation Protein AlphaFluorodeoxyglucose F18Membrane ProteinsRadiopharmaceuticalsAl18F-PET/CTClinical conversionFAP-2286Fibroblast activation protein-α

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.