Evidence map›Paper›PMID 38326606›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2024

Factors affecting early childhood growth in hypoxic-ischemic encephalopathy treated with hypothermia.

Srishti Jayakumar, Vera Joanna Burton, Jamie Perin, Daniella Asafu-Adjaye, Elizabeth Cristofalo, Frances Northington, Raul Chavez-Valdez, Mary Leppert, Marilee Allen, Gwendolyn Gerner

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Srishti JayakumarKennedy Krieger Institute, Department of Neurology and Developmental Medicine, Baltimore, MD, USA. srishtijayakumar@jhu.edu.ORCID 0009-0002-0925-9353
Vera Joanna BurtonKennedy Krieger Institute, Department of Neurology and Developmental Medicine, Baltimore, MD, USA.
Jamie PerinJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.ORCID 0000-0002-5482-6620
Daniella Asafu-AdjayeKennedy Krieger Institute, Department of Neurology and Developmental Medicine, Baltimore, MD, USA.
Elizabeth CristofaloFrederick Memorial Hospital, Department of Neonatology, Frederick, MD, USA.
Frances NorthingtonKennedy Krieger Institute, Department of Neurology and Developmental Medicine, Baltimore, MD, USA.ORCID 0000-0003-4557-2646
Raul Chavez-ValdezKennedy Krieger Institute, Department of Neurology and Developmental Medicine, Baltimore, MD, USA.
Mary LeppertKennedy Krieger Institute, Department of Neurology and Developmental Medicine, Baltimore, MD, USA.
Marilee AllenKennedy Krieger Institute, Department of Neurology and Developmental Medicine, Baltimore, MD, USA.
Gwendolyn GernerKennedy Krieger Institute, Department of Neurology and Developmental Medicine, Baltimore, MD, USA.
Kennedy Krieger Institute · USCalvert Memorial Hospital · USJohns Hopkins University · US

Funding

NEUROLOGY SCIENCES ACADEMIC DEVELOPMENT AWARD (NSADA)K12NS001696 · NINDS · JOHNS HOPKINS UNIVERSITY · PI JOHNSTON, MICHAEL VAN DOREN · 1993 to 2016
$3.8M
Adult Biomarkers in Neonatal Brain Injury and DevelopmentR01HD086058 · NICHD · JOHNS HOPKINS UNIVERSITY · PI EVERETT, ALLEN D, NORTHINGTON, FRANCES J · 2016 to 2020
$3.1M
Advanced therapeutic hypothermia efficacy network modeling in neonatal HIER01HD110091 · NICHD · JOHNS HOPKINS UNIVERSITY · PI EVERETT, ALLEN D, NORTHINGTON, FRANCES J · 2022 to 2025
$2.7M
NICHD NIH HHS R01 HD086058NICHD NIH HHS R01 HD110091NINDS NIH HHS K12 NS001696
6 · The paper itself

Abstract

introductionThere is an extensive body of research regarding neurological outcomes following neonatal hypoxic-ischemic encephalopathy (HIE) treated with therapeutic hypothermia (TH), with limited data on growth outcomes. We examined perinatal characteristics associated with postnatal growth in this population.

methodsConvenience cohort of 66 infants with HIE who underwent TH and participated in follow-up at 24 months of age were included. Regression modeling including perinatal anthropomorphics, markers of HIE, and systemic injury was used to evaluate growth at 24 months.

resultsBirth head circumference was associated with weight (p = 0.036). MRI severity, pH at admission and birth head circumference were associated with height (p = 0.043, p = 0.015 and p = 0.043 respectively). MRI severity and length of intubation were associated with head circumference (p = 0.038 and p < 0.001 respectively).

conclusionThere was a significant association between specific early factors and growth at 24 months among infants with HIE treated with TH.

Indexed as

HypothermiaHypothermia, InducedHypoxia-Ischemia, BrainCephalometryChild, PreschoolFemaleHumansInfantInfant, NewbornPregnancy

Identifiers

PMID38326606
PMCPMC11180224
OpenAlexW4391616898

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.