Evidence map›Paper›PMID 38326577›Full record

ArticleCardiovascular and interventional radiology2024

Lung Mean Dose Prediction in Transarterial Radioembolization (TARE): Superiority of [

Martijn E H M Wagemans, Arthur J A T Braat, Rob van Rooij, Maarten L J Smits, Rutger C G Bruijnen, Jip F Prince, Guus M Bol, Hugo W A M de Jong, Marnix G E H Lam

2 registry-linked trialsAbstract read
In one paragraph

Article in Cardiovascular and interventional radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01031784 phase1completednot on this map

Radioactive Holmium Microspheres for the Treatment of Patients With Non-resectable Liver Metastases of Mixed Origin; a Single Center, Interventional, Non-randomized, Open Label, Safety Study.

TypeinterventionalSponsorUMC UtrechtRan2009 to 2011Enrolled15ConditionsLiver Metastasis, Liver TumorsArmsholmium-166 poly lactic acid microspheres, holmium 166 microspheres
NCT01612325 phase2completednot on this map

Radioactive Holmium Microspheres for the Treatment of Patients With Unresectable Liver Metastases; a Single Center, Interventional, Non-randomized, Phase II (HEPAR II) Trial

TypeinterventionalSponsorUMC UtrechtRan2012 to 2015Enrolled56ConditionsLiver NeoplasmsArmsHolmium-166 polylactic microspheres
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Martijn E H M WagemansDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands. m.e.h.wagemans-2@umcutrecht.nl.ORCID http://orcid.org/0009-0007-3836-2604
Arthur J A T BraatDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Rob van RooijDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Maarten L J SmitsDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Rutger C G BruijnenDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Jip F PrinceDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Guus M BolDepartment of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.
Hugo W A M de JongDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Marnix G E H LamDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRadiation pneumonitis is a serious complication of radioembolization. In holmium-166 ([ MATERIALS AND

methodsPatients were included if they received both scout doses ([

resultsThirty-seven patients with unresectable liver metastases were included. During follow-up, none developed symptoms of radiation pneumonitis. Median eLMD

conclusion[ TRAIL REGISTRATION: NCT01031784, registered December 2009. NCT01612325, registered June 2012.

Indexed as

Embolization, TherapeuticLiver NeoplasmsRadiation PneumonitisHumansLungMicrospheresProspective StudiesRetrospective StudiesTechnetium Tc 99m Aggregated AlbuminTomography, Emission-Computed, Single-PhotonYttrium RadioisotopesTechnetium Tc 99m Aggregated AlbuminYttrium RadioisotopesHolmium-166Lung mean doseRadiation pneumonitisRadioembolizationSPECT/CT

Identifiers

PMID38326577
PMCPMC10997535

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.