Evidence map›Paper›PMID 38326477›Full record

Observational studyPediatric research2024

Defining systolic blood pressure normative values in hospitalized pediatric patients: a single center experience.

Amanda M Uber, Jialin Han, Paul Grimm, Maria E Montez-Rath, Abanti Chaudhuri

Abstract readObservational Study
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Observational study in Pediatric research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Amanda M UberDepartment of Nephrology, Primary Children's Hospital, University of Utah, Salt Lake City, UT, USA.
Jialin HanDepartment of Nephrology, Stanford University School of Medicine, Stanford, CA, USA.
Paul GrimmDepartment of Pediatrics (Nephrology), Stanford University School of Medicine, Stanford, CA, USA.
Maria E Montez-RathDepartment of Nephrology, Stanford University School of Medicine, Stanford, CA, USA.
Abanti ChaudhuriDepartment of Pediatrics (Nephrology), Stanford University School of Medicine, Stanford, CA, USA. abanti@stanford.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNormative blood pressure (BP) values and definition of hypertension (HTN) in children in outpatient setting cannot be reliably used for inpatient therapy initiation. No normative exists to describe HTN in hospitalized pediatric populations. We aimed to study the prevalence of hypertension and produce normative BP values in hospitalized children.

methodsCross sectional observational study of all children hospitalized on acute care floors, ≥2 and <18 years age, at Stanford Children's Hospital, from Jan-01-2014 to Dec-31-2018. Cohort included 7468 hospital encounters with a total of 118,423 automated, oscillometric, BPs measured in the upper extremity during a hospitalization of >24 hours.

resultsOverall prevalence of HTN, defined by outpatient guidelines, was 12-48% in boys and 6-39% in girls, stage 1 systolic HTN in 12-38% of boys and 6-31% of girls, stage 2 systolic HTN in 3-10% of boys and 1-8% of girls. Centile curves were derived demonstrating overall higher BP reading for hospitalized patients compared to the outpatient setting.

conclusionHigher blood pressures are anticipated during hospitalization. Thresholds provided by the centile curves generated in this study may provide the clinician with some guidance on how to manage hospitalized pediatric patients based on clinical circumstances. IMPACT: Hospitalized children have higher blood pressures compared to patients in the ambulatory setting, hence outpatient normative blood pressure values cannot be reliably used for inpatient therapy initiation. No normative exists to describe hypertension in hospitalized pediatric populations. The thresholds provided by the centile curves generated in this study may provide the clinician with some guidance on how to manage hospitalized pediatric patients based on clinical circumstances.

Indexed as

Blood PressureBlood Pressure DeterminationHospitalizationHypertensionAdolescentChildChild, PreschoolCross-Sectional StudiesFemaleHumansMalePrevalenceReference ValuesSystole

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.