Evidence map›Paper›PMID 38326267›Full record

Trial reportBMJ open2024

Can an integrated intervention package including peer support increase the proportion of health facility births? A cluster randomised controlled trial in Northern Uganda.

Victoria Nankabirwa, David Mukunya, Grace Ndeezi, Beatrice Odongkara, Agnes A Arach, Vicentina Achora, Levi Mugenyi, Mohammad Boy Sebit, Julius N Wandabwa, Paul Waako and 2 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02605369 (SURVIVAL PLUSS), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02605369 nacompletednot on this map

SURVIVAL PLUSS: Increasing Capacity for Mama-baby Survival in Post-conflict Uganda and South Sudan

TypeinterventionalSponsorMakerere UniversityRan2018 to 2019Enrolled1,877ConditionsNeonatal Death, Preterm Birth, Low Birthweight, Neonatal HypoglycemiaArmsIntervention arm: An integrated package
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Victoria NankabirwaDepartment of Epidemiology and Biostatistics, Makerere University College of Health Sciences, Kampala, Uganda.
David Mukunya *Busitema University, Tororo, Uganda.ORCID 0000-0002-3892-9777
Grace Ndeezi *Department of Paediatrics and Child Health, Makerere University, Kampala, Uganda gndeezi@gmail.com.ORCID 0000-0001-5557-2733
Beatrice OdongkaraDepartment of Paediatrics and Child Health, Gulu University, Gulu, Uganda.
Agnes A ArachDepartment of Nursing and Midwifery, Lira University, Lira, Uganda.
Vicentina AchoraDepartment of Obstetrics and Gynaecology, Gulu University, Gulu, Uganda.
Levi MugenyiUganda Virus Research Institute, Entebbe, Uganda.
Mohammad Boy SebitDepartment of Psychiatry, University of Juba, Juba, South Sudan.
Julius N WandabwaBusitema University, Tororo, Uganda.
Paul WaakoBusitema University, Tororo, Uganda.
Thorkild TylleskärCentre for International health, Universitetet i Bergen, Bergen, Norway.
James K TumwinePaediatrics and Child Health, Makerere University CHS, Kampala, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the effect of an integrated intervention package compared with routine government health services on the frequency of health facility births.

settingThree subcounties of Lira district in Northern Uganda.

designA cluster randomised controlled trial where a total of 30 clusters were randomised in a ratio of 1:1 to intervention or standard of care.

participantsPregnant women at ≥28 weeks of gestation.

interventionsParticipants in the intervention arm received an integrated intervention package of peer support, mobile phone messaging and birthing kits during pregnancy while those in the control arm received routine government health services ('standard of care'). PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was the proportion of women giving birth at a health facility in the intervention arm compared with the control arm. Secondary outcomes were perinatal and neonatal deaths.

resultsIn 2018-2019, 995 pregnant women were included in 15 intervention clusters and 882 in 15 control clusters. The primary outcome was ascertained for all except one participant who died before childbirth. In the intervention arm, 754/994 participants (76%) gave birth at a health facility compared with 500/882 (57%) in the control arm. Participants in the intervention arm were 35% more likely to give birth at a health facility compared with participants in the control arm, (risk ratio 1.35 (95% CI 1.20 to 1.51)) and (risk difference 0.20 (95% CI 0.13 to 0.27)). Adjusting for baseline differences generated similar results. There was no difference in secondary outcomes (perinatal or neonatal mortality or number of postnatal visits) between arms.

conclusionThe intervention was successful in increasing the proportion of facility-based births but did not reduce perinatal or neonatal mortality. TRIAL REGISTRATION NUMBER: NCT02605369.

Indexed as

Infant MortalityParturitionFemaleHealth FacilitiesHumansInfant, NewbornPostnatal CarePregnancyUgandaNEONATOLOGYOrganisation of health servicesReproductive medicine

Identifiers

PMID38326267
PMCPMC10860059

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.