ArticleBMJ (Clinical research ed.)2024
Duration of cardiopulmonary resuscitation and outcomes for adults with in-hospital cardiac arrest: retrospective cohort study.
Article in BMJ (Clinical research ed.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Outcomes of odontoid fractures with associated cardiac arrest: retrospective bi-center case series and systematic literature review.Scandinavian journal of trauma, resuscitation and emergency medicine · 2024Pooled it
- Sudden cardiac death in younger adults: a comparative analysis of coronary and non-coronary causes.International journal of cardiology. Heart & vasculature · 2026Article
- In-Hospital Cardiac Resuscitation During Widespread Resident Resignations in South Korea.JAMA network open · 2026Article
- Article
- Esmolol in the management of refractory ventricular fibrillation: a systematic review and meta-analysis.Acute and critical care · 2026Article
- Why Post-Cardiac Arrest Interventions Often Fail: Therapeutic Amenability and the Rapidly Closing Window of Neuroprotection.Journal of clinical medicine · 2026Review
- Neural Response to Familiar Names Predicts Outcome of Comatose ICU Patients: A Prospective Observational Cohort Study.Nature communications · 2026Observational
- Resuscitation in Oncology: Limits, Ethics, Practice, and Humanity.Current oncology (Toronto, Ont.) · 2026Review
- External validation of rules for termination of resuscitation in in-hospital cardiac arrest.Resuscitation · 2026Observational
- Implementation of emergency extracorporeal membrane oxygenation in a hospital without on-site cardiothoracic surgery support.Resuscitation plus · 2026Article
- Serial lactate-procalcitonin interaction identifies a high-risk phenotype in 24-h conditional survivors of post-cardiac arrest syndrome: a CART-based analysis.Frontiers in medicine · 2026Article
- Wolf Creek XVIII Part 2: optimizing time intervals in cardiac arrest care.Resuscitation plus · 2026Review
- Pharmacological mechanisms and clinical evidence of vasopressin, steroids, and epinephrine triple therapy in in-hospital cardiac arrest.Frontiers in cardiovascular medicine · 2026Review
- Utilization and outcomes of cardiopulmonary resuscitated donor hearts in the modern era.JTCVS open · 2025Article
- Setting the Next Vital Sign Observation Interval as a Learning Objective in Simulation-Based Nursing Education: A Prospective Exploratory Observational Study.Nursing reports (Pavia, Italy) · 2025Article
- In-hospital cardiac arrest - A three-year Utstein- style report from a tertiary care centre in Poland.Resuscitation plus · 2025Article
- POTEC (Platelet Count, Oxygen Saturation, Time of CPR, Elective Surgery, and Initial ETCOJournal of clinical medicine · 2025Article
- Article
- Real-Time Predictors of Return of Spontaneous Circulation in an Emergency Setting: A Five-Year Retrospective Study.Diagnostics (Basel, Switzerland) · 2025Article
- Extracorporeal CPR Performance Metrics in Adult In-Hospital Cardiac Arrest: A Stepwise and Evidence-Based Appraisal of the VA-ECMO Implementation Process.Journal of clinical medicine · 2025Review
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 6 institutions in 4 countries.
Funding
Abstract
objectiveTo quantify time dependent probabilities of outcomes in patients after in-hospital cardiac arrest as a function of duration of cardiopulmonary resuscitation, defined as the interval between start of chest compression and the first return of spontaneous circulation or termination of resuscitation.
designRetrospective cohort study.
settingMulticenter prospective in-hospital cardiac arrest registry in the United States.
participants348 996 adult patients (≥18 years) with an index in-hospital cardiac arrest who received cardiopulmonary resuscitation from 2000 through 2021.
main outcome measuresSurvival to hospital discharge and favorable functional outcome at hospital discharge, defined as a cerebral performance category score of 1 (good cerebral performance) or 2 (moderate cerebral disability). Time dependent probabilities of subsequently surviving to hospital discharge or having favorable functional outcome if patients pending the first return of spontaneous circulation at each minute received further cardiopulmonary resuscitation beyond the time point were estimated, assuming that all decisions on termination of resuscitation were accurate (that is, all patients with termination of resuscitation would have invariably failed to survive if cardiopulmonary resuscitation had continued for a longer period of time).
resultsAmong 348 996 included patients, 233 551 (66.9%) achieved return of spontaneous circulation with a median interval of 7 (interquartile range 3-13) minutes between start of chest compressions and first return of spontaneous circulation, whereas 115 445 (33.1%) patients did not achieve return of spontaneous circulation with a median interval of 20 (14-30) minutes between start of chest compressions and termination of resuscitation. 78 799 (22.6%) patients survived to hospital discharge. The time dependent probabilities of survival and favorable functional outcome among patients pending return of spontaneous circulation at one minute's duration of cardiopulmonary resuscitation were 22.0% (75 645/343 866) and 15.1% (49 769/328 771), respectively. The probabilities decreased over time and were <1% for survival at 39 minutes and <1% for favorable functional outcome at 32 minutes' duration of cardiopulmonary resuscitation.
conclusionsThis analysis of a large multicenter registry of in-hospital cardiac arrest quantified the time dependent probabilities of patients' outcomes in each minute of duration of cardiopulmonary resuscitation. The findings provide resuscitation teams, patients, and their surrogates with insights into the likelihood of favorable outcomes if patients pending the first return of spontaneous circulation continue to receive further cardiopulmonary resuscitation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.