Evidence map›Paper›PMID 38325698›Full record

ArticleJournal of biomedical informatics2024

SPeC: A Soft Prompt-Based Calibration on Performance Variability of Large Language Model in Clinical Notes Summarization.

Yu-Neng Chuang, Ruixiang Tang, Xiaoqian Jiang, Xia Hu

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Journal of healthcare informatics research · 2025
    Article
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  6. Review
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  14. Towards Fair Patient-Trial Matching via Patient-Criterion Level Fairness Constraint.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yu-Neng ChuangRice University, Houston, TX, United States of America. Electronic address: yc146@rice.edu.
Ruixiang TangRice University, Houston, TX, United States of America.
Xiaoqian JiangUniversity of Texas Health Science Center, Houston, TX, United States of America.
Xia HuRice University, Houston, TX, United States of America. Electronic address: xia.hu@rice.edu.

Funding

AIM-AHEAD Coordinating Center - All Four CoresOT2OD032581 · OD · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI Paul Avillach, Bettina M. Beech · 2021 to 2026
$168.7M
RADx-Rad Discoveries & Data: Consortium Coordination Center Program OrganizationU24LM013755 · NLM · YALE UNIVERSITY · PI ARONOFF-SPENCER, ELIAH S, OHNO-MACHADO, LUCILA · 2021 to 2023
$23.3M
Ethics Core (FABRIC)U54HG012510 · NHGRI · YALE UNIVERSITY · PI MALIN, BRADLEY A. · 2022 to 2025
$11.2M
Open Health Natural Language Processing CollaboratoryU01TR002062 · NCATS · MAYO CLINIC ROCHESTER · PI JIANG, XIAOQIAN, LIU, HONGFANG · 2017 to 2021
$7.6M
AIM-AI: an Actionable, Integrated and Multiscale genetic map of Alzheimer's disease via deep learningU01AG079847 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Christopher A. Gaiteri, Xiaoqian Jiang · 2023 to 2026
$5.1M
Finding Combinatorial Drug Repositioning Therapy For Alzheimer'S Disease And Related DementiasR01AG066749 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI JIANG, XIAOQIAN, ZHENG, WENJIN JIM · 2020 to 2024
$4.4M
Accelerating Genomic Data Sharing and Collaborative Research with Privacy ProtectionR01LM014520 · NLM · CASE WESTERN RESERVE UNIVERSITY · PI Erman Ayday, Xiaoqian Jiang · 2023 to 2026
$2.6M
Decentralized differentially-private methods for dynamic data release and analysisR01LM013712 · NLM · YALE UNIVERSITY · PI JIANG, XIAOQIAN, OHNO-MACHADO, LUCILA · 2022 to 2025
$2.5M
Harmonizing multiple clinical trials for Alzheimer's disease to investigate differential responses to treatment via federated counterfactual learningR01AG082721 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Xiaoqian Jiang, Yejin Kim · 2023 to 2026
$2.0M
Robust privacy preserving distributed analysis platform for cancer research: addressing data bias and disparitiesU01CA274576 · NCI · UNIVERSITY OF PENNSYLVANIA · PI JIANG, XIAOQIAN, LONG, QI · 2023 to 2025
$1.2M
NCATS NIH HHS U01 TR002062NCI NIH HHS U01 CA274576NHGRI NIH HHS U54 HG012510NIA NIH HHS R01 AG066749NIA NIH HHS R01 AG082721NIA NIH HHS U01 AG079847NIH HHS OT2 OD032581NLM NIH HHS R01 LM013712NLM NIH HHS R01 LM014520NLM NIH HHS U24 LM013755
6 · The paper itself

Abstract

Electronic health records (EHRs) store an extensive array of patient information, encompassing medical histories, diagnoses, treatments, and test outcomes. These records are crucial for enabling healthcare providers to make well-informed decisions regarding patient care. Summarizing clinical notes further assists healthcare professionals in pinpointing potential health risks and making better-informed decisions. This process contributes to reducing errors and enhancing patient outcomes by ensuring providers have access to the most pertinent and current patient data. Recent research has shown that incorporating instruction prompts with large language models (LLMs) substantially boosts the efficacy of summarization tasks. However, we show that this approach also leads to increased performance variance, resulting in significantly distinct summaries even when instruction prompts share similar meanings. To tackle this challenge, we introduce a model-agnostic Soft Prompt-BasedCalibration (SPeC) pipeline that employs soft prompts to lower variance while preserving the advantages of prompt-based summarization. Experimental findings on multiple clinical note tasks and LLMs indicate that our method not only bolsters performance but also effectively regulates variance across different LLMs, providing a more consistent and reliable approach to summarizing critical medical information.

Indexed as

Electronic Health RecordsNatural Language ProcessingCalibrationHealth PersonnelHumansLanguageClinical research informaticsData miningKnowledge representation and information modelingMachine learningNatural language processing

Identifiers

PMID38325698
PMCPMC11608453

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.