ReviewCell genomics2024
The Mutographs biorepository: A unique genomic resource to study cancer around the world.
Abstract readReview
In one paragraph
Review in Cell genomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Brazilian biorepository to support genome-wide association studies of colorectal, breast, and cervical cancer.iScience · 2026Article
- Centralized processing of frozen tumor tissues for global cancer genomics.Nature protocols · 2026Review
- Reconstructing the lifelong history of cells and tissues via somatic mutation analysis.Cellular and molecular life sciences : CMLS · 2025Review
- Blocking CXCR4Genome medicine · 2025Article
- Article
- Tobacco smoke carcinogens exacerbate APOBEC mutagenesis and carcinogenesis.Research square · 2025Article
- DiffInvex identifies evolutionary shifts in driver gene repertoires during tumorigenesis and chemotherapy.Nature communications · 2025Article
- Genomic landscape of cancer in racially and ethnically diverse populations.Nature reviews. Genetics · 2025Review
- The complexity of tobacco smoke-induced mutagenesis in head and neck cancer.Nature genetics · 2025Article
- Geographic and age-related variations in mutational processes in colorectal cancer.medRxiv : the preprint server for health sciences · 2025Article
- Colorectal Cancer: Current and Future Therapeutic Approaches and Related Technologies Addressing Multidrug Strategies Against Multiple Level Resistance Mechanisms.International journal of molecular sciences · 2025Review
- Tobacco smoke carcinogens exacerbate APOBEC mutagenesis and carcinogenesis.bioRxiv : the preprint server for biology · 2025Article
- Implementing Mutational Epidemiology on a Global Scale: Lessons from Mutographs.Cancer discovery · 2025Article
- Methods and applications of genome-wide profiling of DNA damage and rare mutations.Nature reviews. Genetics · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
74 authors.
Sandra PerdomoGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Behnoush Abedi-ArdekaniGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Ana Carolina de CarvalhoGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Aida Ferreiro-IglesiasGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Valérie GaborieauGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Thomas CattiauxGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Hélène RenardGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Priscilia ChopardGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Christine CarreiraEvidence Synthesis and Classification Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Andreea SpanuGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Arash NikmaneshGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Ricardo Cortez Cardoso PenhaGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Samuel O AntwiDivision of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA.
Patricia Ashton-ProllaExperimental Research Center, Genomic Medicine Laboratory, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil; Post-Graduate Program in Genetics and Molecular Biology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Cristina CanovaUnit of Biostatistics, Epidemiology and Public Health, Department of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padua, Padova, Italy.
Taned ChitapanaruxDepartment of Internal Medicine, Chiang Mai University, Chiang Mai, Thailand.
Riley CoxOntario Tumour Bank, Ontario Institute for Cancer Research, Toronto, ON, Canada.
Maria Paula CuradoDepartment of Epidemiology, A.C. Camargo Cancer Center, São Paulo, Brazil.
José Carlos de OliveiraAssociação de Combate ao Câncer em Goiás Hospital Araújo Jorge Goiânia, Goiânia, Brazil.
Charles DzamalalaUniversity of Malawi College of Medicine, Blantyre, Malawi.
Elenora FabianovaRegional Authority of Public Health, Banská Bystrica, Slovakia.
Lorenzo FerriDepartments of Surgery and Oncology, McGill University, Montreal, QC, Canada.
Rebecca FitzgeraldEarly Cancer Institute, University of Cambridge, Cambridge, UK.
Lenka ForetovaDepartment of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic.
Steven GallingerMount Sinai Hospital; Ontario Institute for Cancer Research (OICR), Toronto, ON, Canada.
Alisa M GoldsteinDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Ivana HolcatovaInstitute of Public Health & Preventive Medicine, 2nd Faculty of Medicine, Charles University, Prague, Czech Republic; Department of Oncology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
Antonio HuertasNational Cancer Institute, Bogotá, Colombia.
Vladimir JanoutFaculty of Health Sciences, Palacky University, Olomouc, Czech Republic.
Sonata JarmalaiteLaboratory of Genetic Diagnostic, National Cancer Institute, Vilnius, Lithuania; Department of Botany and Genetics, Institute of Biosciences, Vilnius University, Vilnius, Lithuania.
Radka KanevaMolecular Medicine Center, Department of Medical Chemistry and Biochemistry, Medical Faculty, Medical University of Sofia, Sofia, Bulgaria.
Luiz Paulo KowalskiDepartment of Epidemiology, A.C. Camargo Cancer Center, São Paulo, Brazil; University of São Paulo Medical School, São Paulo, Brazil.
Tomislav KulisDepartment of Urology, University Hospital Center Zagreb, Zagreb, Croatia; University of Zagreb School of Medicine, Zagreb, Croatia.
Pagona LagiouNational and Kapodistrian University of Athens, Athens, Greece.
Jolanta LissowskaThe Maria Sklodowska-Cure National Research Institute of Oncology, Warsaw, Poland.
Reza MalekzadehDigestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Dana MatesOccupational Health and Toxicology, National Center for Environmental Risk Monitoring, National Institute of Public Health, Bucharest, Romania.
Valerie McCorrmackEnvironment and Lifestyle Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Diana MenyaMoi University, School of Public Health, Eldoret, Kenya.
Sharayu MhatreDivision of Molecular Epidemiology and Population Genomics, Centre for Cancer Epidemiology, Tata Memorial Centre, Mumbai, India.
Blandina Theophil MmbagaDepartment of Surgery, Santa Casa School of Medicine, São Paulo, Brazil.
André de MoriczKilimanjaro Clinical Research Institute, Kilimanjaro Christian Medical Centre & Kilimanjaro Christian Medical University College, Moshi, Tanzania.
Péter NyirádySemmelweis University, Budapest, Hungary.
Miodrag OgnjanovicIOCPR- International Organization for Cancer Prevention and Research, Serbia, Belgrade.
Kyriaki PapadopoulouHellenic Cooperative Oncology Group (HeCOG), Athens, Greece.
Jerry PoleselCentro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.
Mark P PurdueDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Stefan RascuUrology Department, "Carol Davila" University of Medicine and Pharmacy - "Prof. Dr. Th. Burghele" Clinical Hospital, Bucharest, Romania.
Lidia Maria Rebolho BatistaMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil.
Rui Manuel ReisMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil; Life and Health Sciences Research Institute (ICVS), School of Medicine, Minho University, Braga, Portugal.
Luis Felipe Ribeiro PintoBrazilian National Cancer Institute, Rio de Janeiro, Brazil.
Paula A Rodríguez-UrregoPathology Department, Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, Colombia.
Surasak SangkhathatTranslational Medicine Research Center, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.
Suleeporn SangrajrangNational Cancer Institute, Bangkok, Thailand.
Tatsuhiro ShibataLaboratory of Molecular Medicine, The Institute of Medical Science, The University of Tokyo, Minato-ku, Japan; Division of Cancer Genomics, National Cancer Center Research Institute, Chuo-ku, Japan.
Eduard StakhovskyNational Cancer Institute, Kiev, Ukraine.
Beata ŚwiątkowskaDepartment of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Łódź, Poland.
Carlos VaccaroInstituto Medicina Traslacional e Ingenieria Biomedica - CONICET, Buenos Aires, Argentina.
Jose Roberto Vasconcelos de PodestaHospital Santa Rita AFECC - Associação Feminina de Educação e Combate ao Câncer, Vitoria, Brazil.
Naveen S VasudevLeeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Marta VilenskyInstituto de Oncología Angel Roffo, Universidad de Buenos Aires, Buenos Aires, Argentina.
Jonathan YeungUniversity Health Network, Toronto, ON, Canada.
David ZaridzeClinical Epidemiology, N.N. Blokhin National Medical Research Centre of Oncology, Moscow, Russia.
Kazem ZendehdelCancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Ghislaine SceloObservational & Pragmatic Research Institute Pte., Ltd., Singapore, Singapore.
Estelle ChanudetDepartment of Pathology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Jingwei WangCancer, Ageing and Somatic Mutation, Wellcome Sanger Institute, Cambridge, UK.
Stephen FitzgeraldCancer, Ageing and Somatic Mutation, Wellcome Sanger Institute, Cambridge, UK.
Calli LatimerCancer, Ageing and Somatic Mutation, Wellcome Sanger Institute, Cambridge, UK.
Sarah MoodyCancer, Ageing and Somatic Mutation, Wellcome Sanger Institute, Cambridge, UK.
Laura HumphreysCancer, Ageing and Somatic Mutation, Wellcome Sanger Institute, Cambridge, UK.
Ludmil B AlexandrovDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA; Moores Cancer Center, University of California San Diego, La Jolla, CA, USA.
Michael R StrattonCancer, Ageing and Somatic Mutation, Wellcome Sanger Institute, Cambridge, UK.
Paul BrennanGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France. Electronic address: brennanp@iarc.who.int.
Funding
Data sharing: the Colon Cancer Family Registry CohortU01CA167551 · NCI · UNIVERSITY OF MELBOURNE · PI Daniel David BUCHANAN, Steven Gallinger · 2018 to 2026
$16.8MEsophageal cancer genetic projectZIACP010224 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI GOLDSTEIN, ALISA · 2012 to 2025
$7.3MEsophageal cancer in West KenyaR21CA191965 · NCI · INTERNATIONAL AGENCY FOR RES ON CANCER · PI MCCORMACK, VALERIE · 2015 to 2016
$256kCancer Research UK 27145NCI NIH HHS R21 CA191965NCI NIH HHS U01 CA167551Wellcome TrustWorld Health Organization 001
Abstract
Large-scale biorepositories and databases are essential to generate equitable, effective, and sustainable advances in cancer prevention, early detection, cancer therapy, cancer care, and surveillance. The Mutographs project has created a large genomic dataset and biorepository of over 7,800 cancer cases from 30 countries across five continents with extensive demographic, lifestyle, environmental, and clinical information. Whole-genome sequencing is being finalized for over 4,000 cases, with the primary goal of understanding the causes of cancer at eight anatomic sites. Genomic, exposure, and clinical data will be publicly available through the International Cancer Genome Consortium Accelerating Research in Genomic Oncology platform. The Mutographs sample and metadata biorepository constitutes a legacy resource for new projects and collaborations aiming to increase our current research efforts in cancer genomic epidemiology globally.
Indexed as
NeoplasmsBiological Specimen BanksDatabases, FactualDelivery of Health CareGenomicsHumans
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.