ReviewEmerging infectious diseases2024
Concurrent Clade I and Clade II Monkeypox Virus Circulation, Cameroon, 1979-2022.
Review in Emerging infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Pooled it
- Mpox vaccine acceptance and uptake in Africa: a systematic review and meta-analysis.BMC global and public health · 2026Pooled it
- Global and regional mortality rate statistics of mpox (formerly monkeypox): a comprehensive systematic review and meta-analysis.Pathogens and global health · 2025Pooled it
- Global epidemiology, viral evolution, and public health responses: a systematic review on Mpox (1958-2024).Journal of global health · 2025Pooled it
- Epidemiological, clinical and virological profile of Mpox in Kinshasa, democratic republic of the Congo, 2024-2025: a cross-sectional study.BMC infectious diseases · 2026Article
- Pathogenic signatures and therapeutic evaluation of emergent MPXV Clade Ib in low-susceptibility and immunocompromised mouse models.BMC microbiology · 2026Article
- Evidence of monkeypox virus clade IIb lineage A.2.2 in the Republic of the Congo and co-circulation of clade Ia, Ib and clade IIb.Nature medicine · 2026Article
- Evaluation and Clinical Validation of Pan-Specific and Clade-Specific Diagnostic Real-Time PCR Assays for Monkeypox Virus.Journal of medical virology · 2026Article
- An Adaptive Generative 3D VNet Model for Enhanced Monkeypox Lesion Classification Using Deep Learning and Augmented Image Fusion.Journal of imaging informatics in medicine · 2026Article
- Efficient whole-genome sequencing of Monkeypox virus using a novel nuclease-multiple displacement amplification enrichment method.Npj viruses · 2026Article
- Mpox coinfections and clinical manifestation in Africa: a systematic review and meta-analysis.Frontiers in systems biology · 2026Review
- Unveiling Intra-Clonal Diversity of Monkeypox Virus from Brazil's First Outbreak Wave.Viruses · 2025Article
- Squirrel reservoirs of monkeypox virus are sister species separated by the Sanaga River (Cameroon), as are the two main viral clades.One health (Amsterdam, Netherlands) · 2025Article
- From forest to frontline: A comprehensive review of Mpox's global leap and viral evolution (2022-2024).One health (Amsterdam, Netherlands) · 2025Review
- Development and validation of a new mpox virus sequencing and bioinformatic analysis pipeline.Emerging microbes & infections · 2025Article
- Mpox surveillance in endemic regions: a scoping review of trends, challenges, and recommendations.BMC infectious diseases · 2025Article
- Tracking the evolutionary footprint of Mpox in West Africa: phylogenetic and clade analysis.Epidemiology and infection · 2025Article
- Mpox: What Have We Learned and How Do We Better Prepare for the Future?The Journal of infectious diseases · 2025Article
- Clade Ib Mpox Virus: How Can We Respond?China CDC weekly · 2025Article
- Article
Corrections and comments
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Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During 1979-2022, Cameroon recorded 32 laboratory-confirmed mpox cases among 137 suspected mpox cases identified by the national surveillance network. The highest positivity rate occurred in 2022, indicating potential mpox re-emergence in Cameroon. Both clade I (n = 12) and clade II (n = 18) monkeypox virus (MPXV) were reported, a unique feature of mpox in Cameroon. The overall case-fatality ratio of 2.2% was associated with clade II. We found mpox occurred only in the forested southern part of the country, and MPXV phylogeographic structure revealed a clear geographic separation among concurrent circulating clades. Clade I originated from eastern regions close to neighboring mpox-endemic countries in Central Africa; clade II was prevalent in western regions close to West Africa. Our findings suggest that MPXV re-emerged after a 30-year lapse and might arise from different viral reservoirs unique to ecosystems in eastern and western rainforests of Cameroon.
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Registered trials
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