Evidence map›Paper›PMID 38324908›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2024

Serial Mass Screening for Tuberculosis Among Incarcerated Persons in Brazil.

Rafaele Carla Pivetta de Araujo, Leonardo Martinez, Andrea da Silva Santos, Everton Ferreira Lemos, Roberto Dias de Oliveira, Mariana Croda, Dâmaris Porto Batestin Silva, Isabella Beatriz Gonçalves Lemes, Eunice Atsuko Totumi Cunha, Thais Oliveira Gonçalves and 5 more

Erratum issued Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07520448 (Prevention and Mass Screening of TB in Prisons in Paraguay), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07520448 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Prevention and Mass Screening of TB in Prisons in Paraguay (PRESMAP-TB)

TypeinterventionalSponsorUniversidad Nacional de CaaguazuRan2026 to 2028Enrolled4,500ConditionsTuberculosis (TB), TB Infection, Prisoners, EpidemiologyArmsType 1 - Intensive Intervention, Type 2 - Optimized intervention, Type 3. Control.
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Lancet regional health. Americas · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Effectiveness of Systematic Screening and Treatment of Tuberculosis in Prison in Thailand.The American journal of tropical medicine and hygiene · 2024
    Article
  12. Article
  13. For Tuberculosis, Not "To Screen or Not to Screen?" but "Who?" and "How?"Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Rafaele Carla Pivetta de AraujoHealth Sciences Research Laboratory, Federal University of Grande Dourados, Dourados, Brazil.ORCID 0000-0002-1474-5236
Leonardo MartinezDepartment of Epidemiology, School of Public Health, Boston University, Boston, Massachusetts, USA.
Andrea da Silva SantosHealth Sciences Research Laboratory, Federal University of Grande Dourados, Dourados, Brazil.
Everton Ferreira LemosSchool of Medicine, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Roberto Dias de OliveiraNursing Course, State University of Mato Grosso do Sul, Dourados, Brazil.
Mariana CrodaSchool of Medicine, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Dâmaris Porto Batestin SilvaSchool of Medicine, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Isabella Beatriz Gonçalves LemesSchool of Medicine, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Eunice Atsuko Totumi CunhaLaboratory of Bacteriology, Central Laboratory of Mato Grosso do Sul, Campo Grande, Mato Gross do Sul, Brazil.
Thais Oliveira GonçalvesLaboratory of Bacteriology, Central Laboratory of Mato Grosso do Sul, Campo Grande, Mato Gross do Sul, Brazil.
Paulo Cesar Pereira Dos SantosSchool of Medicine, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Bruna Oliveira da SilvaHealth Sciences Research Laboratory, Federal University of Grande Dourados, Dourados, Brazil.
Crhistinne Cavalheiro Maymone GonçalvesSchool of Medicine, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Jason AndrewsDivision of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California, USA.
Julio CrodaSchool of Medicine, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Universidade Federal de Mato Grosso do Sul · BRUniversidade Federal da Grande Dourados · BRBoston University · USStanford University · US

Funding

Strategies for tuberculosis control in prisonsR01AI130058 · NIAID · STANFORD UNIVERSITY · PI Jason Randolph Andrews, Julio Henrique Rosa Croda · 2017 to 2026
$5.8M
Identifying effective and efficient approaches to tuberculosis screening in BrazilianprisonsK01AI156022 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MARTINEZ, LEONARDO · 2021 to 2025
$640k
Characterizing infectiousness of subclinical TB and identifying novel early diagnostic strategies for preventing transmissionR01AI149620 · NIAID · STANFORD UNIVERSITY · PI ANDREWS, JASON RANDOLPH, CRODA, JULIO · 2020 to 2023
$617k
National Council for Scientific and Technological DevelopmentNIAID NIH HHS K01 AI156022NIAID NIH HHS R01 AI130058NIAID NIH HHS R01 AI149620State Secretary of Health of Mato Grosso do Sul
6 · The paper itself

Abstract

backgroundAn active search for tuberculosis cases through mass screening is widely described as a tool to improve case detection in hyperendemic settings. However, its effectiveness in high-risk populations, such as incarcerated people, is debated.

methodsBetween 2017 and 2021, 3 rounds of mass screening were carried out in 3 Brazilian prisons. Social and health questionnaires, chest X-rays, and Xpert MTB/RIF were performed.

resultsMore than 80% of the prison population was screened. Overall, 684 cases of pulmonary tuberculosis were diagnosed. Prevalence across screening rounds was not statistically different. Among incarcerated persons with symptoms, the overall prevalence of tuberculosis per 100 000 persons was 8497 (95% confidence interval [CI], 7346-9811), 11 115 (95% CI, 9471-13 082), and 7957 (95% CI, 6380-9882) in screening rounds 1, 2, and 3, respectively. Similar to our overall results, there were no statistical differences between screening rounds and within individual prisons. We found no statistical differences in Computer-Aided Detection for TB version 5 scores across screening rounds among people with tuberculosis-the median scores in rounds 1, 2, and 3 were 82 (interquartile range [IQR], 63-97), 77 (IQR, 60-94), and 81 (IQR, 67-92), respectively.

conclusionsIn this environment with hyperendemic rates of tuberculosis, 3 rounds of mass screening did not reduce the overall tuberculosis burden. In prisons, where a substantial number of tuberculosis cases is undiagnosed annually, a range of complementary interventions and more frequent tuberculosis cases screening may be required.

Indexed as

Mass ScreeningPrisonersPrisonsTuberculosis, PulmonaryAdultBrazilFemaleHumansMaleMiddle AgedMycobacterium tuberculosisPrevalenceTuberculosisYoung Adultincarcerationmass screeningtuberculosis

Identifiers

PMID38324908
PMCPMC11175667
OpenAlexW4391664497

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.