Evidence map›Paper›PMID 38324547›Full record

ArticlePloS one2024

How does COVID-19 vaccination affect long-COVID symptoms?

Ali A Asadi-Pooya, Meshkat Nemati, Mina Shahisavandi, Hamid Nemati, Afrooz Karimi, Anahita Jafari, Sara Nasiri, Seyyed Saeed Mohammadi, Zahra Rahimian, Hossein Bayat and 3 more

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Maladaptive trained immunity in viral infections.The Journal of clinical investigation · 2025
    Review
  4. Article
  5. From Stagnation to Strategy: Challenges in Advancing Long COVID Research.Journal of evaluation in clinical practice · 2025
    Review
  6. Incidence of Long COVID Diagnoses in 3.6 Million U.S. Medicare Beneficiaries With COVID-19.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Inflammatory pathways in patients with post-acute sequelae of COVID-19: The role of the clinical immunologist.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
    Review
  11. Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ali A Asadi-PooyaEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0002-2598-7601
Meshkat NematiEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Mina ShahisavandiEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Hamid NematiEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Afrooz KarimiEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0002-5003-5645
Anahita JafariEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Sara NasiriEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Seyyed Saeed MohammadiEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Zahra RahimianEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Hossein BayatEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Ali AkbariDepartment of Anesthesiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Amir EmamiBurn & Wound Healing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0002-4510-1820
Owrang EilamiHIV and AIDS Research Center, Department of Infectious Disease and Family Medicine, Shiraz University of Medical Science, Shiraz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe current study aimed to identify the association between COVID-19 vaccination and prolonged post-COVID symptoms (long-COVID) in adults who reported suffering from this condition.

methodsThis was a retrospective follow-up study of adults with long-COVID syndrome. The data were collected during a phone call to the participants in January-February 2022. We inquired about their current health status and also their vaccination status if they agreed to participate.

resultsIn total, 1236 people were studied; 543 individuals reported suffering from long long- COVID (43.9%). Chi square test showed that 15 out of 51 people (29.4%) with no vaccination and 528 out of 1185 participants (44.6%) who received at least one dose of any vaccine had long long- COVID symptoms (p = 0.032).

conclusionsIn people who have already contracted COVID-19 and now suffer from long-COVID, receiving a COVID vaccination has a significant association with prolonged symptoms of long-COVID for more than one year after the initial infection. However, vaccines reduce the risk of severe COVID-19 (including reinfections) and its catastrophic consequences (e.g., death). Therefore, it is strongly recommended that all people, even those with a history of COVID-19, receive vaccines to protect themselves against this fatal viral infection.

Indexed as

COVID-19Post-Acute COVID-19 SyndromeAdultCOVID-19 VaccinesFollow-Up StudiesHumansRetrospective StudiesVaccinationCOVID-19 Vaccines

Identifiers

PMID38324547
PMCPMC10849259

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.