Evidence map›Paper›PMID 38324518›Full record

ArticlePloS one2024

Prevalence of DSM-5 mild and major neurocognitive disorder in India: Results from the LASI-DAD.

Alden L Gross, Emma Nichols, Marco Angrisani, Mary Ganguli, Haomiao Jin, Pranali Khobragade, Kenneth M Langa, Erik Meijer, Mathew Varghese, A B Dey and 1 more

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  8. Efficacy ofJMIR research protocols · 2026
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  10. Missing data and imputation in the international studies following the Harmonized Cognitive Assessment Protocol.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
  11. Ethnic Differences in the Association Between Cognitive Performance and Informant-rated Cognitive Decline.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2025
    Article
  12. Article
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  14. Care Need, Caregiver Availability, and Care Receipt: Variations Across Countries and Over Time in Three Middle-Income Countries.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
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  17. Mental Health Impacts of COVID-19: Does Prepandemic Cognition and Dementia Status Matter?The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alden L GrossDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.ORCID 0000-0002-4678-0562
Emma NicholsCenter for Economic and Social Research, University of Southern California, Los Angeles, Los Angeles, California, United States of America.ORCID 0000-0002-9005-3872
Marco AngrisaniCenter for Economic and Social Research, University of Southern California, Los Angeles, Los Angeles, California, United States of America.
Mary GanguliDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
Haomiao JinSchool of Health Sciences, University of Surrey, Guildford, United Kingdom.
Pranali KhobragadeDepartment of Economics, University of Southern California, Los Angeles, Los Angeles, California, United States of America.
Kenneth M LangaDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, United States of America.
Erik MeijerCenter for Economic and Social Research, University of Southern California, Los Angeles, Los Angeles, California, United States of America.ORCID 0000-0001-7959-4670
Mathew VargheseDepartment of Psychiatry, St. John's Medical College, Bengaluru, Karnataka, India.
A B DeyVenu Geriatric Institute, New Delhi, India.
Jinkook LeeCenter for Economic and Social Research, University of Southern California, Los Angeles, Los Angeles, California, United States of America.

Funding

Integrting Information About Aging SurveysR01AG030153 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Sara Adar, Alden L. Gross · 2007 to 2026
$41.7M
Leveraging a natural experiment to estimate the causal impact of blood sugar on dementia and cognition in IndiaR01AG051125 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jinkook Lee · 2015 to 2026
$26.8M
Harmonized Diagnostic Assessment of Dementia (DAD) for Longitudinal Aging Study of India (LASI)-Genomic study.U01AG064948 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KARDIA, SHARON L, LEE, JINKOOK · 2019 to 2023
$12.5M
Socioeconomic, Cardiovascular, and Psychosocial Sources of Cross-National Variation in Cognitive Health Among Older AdultsR01AG070953 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Alden L. Gross, Lindsay C Kobayashi · 2021 to 2026
$4.6M
NIA NIH HHS R01 AG030153NIA NIH HHS R01 AG051125NIA NIH HHS R01 AG070953NIA NIH HHS U01 AG064948
6 · The paper itself

Abstract

introductionIndia, with its rapidly aging population, faces an alarming burden of dementia. We implemented DSM-5 criteria in large-scale, nationally representative survey data in India to characterize the prevalence of mild and major Neurocognitive disorder.

methodsThe Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India (LASI-DAD) (N = 4,096) is a nationally representative cohort study in India using multistage area probability sampling methods. Using neuropsychological testing and informant reports, we defined DSM-5 mild and major neurocognitive disorder, reported its prevalence, and evaluated criterion and construct validity of the algorithm using clinician-adjudicated Clinical Dementia Ratings (CDR)®.

resultsThe prevalence of mild and major neurocognitive disorder, weighted to the population, is 17.6% and 7.2%. Demographic gradients with respect to age and education conform to hypothesized patterns. Among N = 2,390 participants with a clinician-adjudicated CDR, CDR ratings and DSM-5 classification agreed for N = 2,139 (89.5%) participants. DISCUSSION: The prevalence of dementia in India is higher than previously recognized. These findings, coupled with a growing number of older adults in the coming decades in India, have important implications for society, public health, and families. We are aware of no previous Indian population-representative estimates of mild cognitive impairment, a group which will be increasingly important in coming years to identify for potential therapeutic treatment.

Indexed as

Cognitive DysfunctionDementiaAgedAgingCohort StudiesHumansIndiaNeuropsychological TestsPrevalence

Identifiers

PMID38324518
PMCPMC10849236

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.