ArticleAdvanced healthcare materials2024
Flexible Polymer Electrodes for Stable Prosthetic Visual Perception in Mice.
Article in Advanced healthcare materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Repeatable, low-drift recordings in behaving nonhuman primates using flexible microelectrodes.Nature communications · 2026Article
- Learning induces activation-mechanism-dependent neural plasticity in an intracortical microstimulation task.Science advances · 2026Article
- Friend, Not Foe: Lowered Tissue Reactivity to Long-Term Polyimide Implants.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Friend, not Foe: Lowered Tissue Reactivity to Long-Term Polyimide Implants.bioRxiv : the preprint server for biology · 2026Article
- PEDOT:PSS-A Key Material for Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Neural mechanisms underlying intracortical microstimulation for sensory restoration.Nature biomedical engineering · 2026Review
- Revolutionizing brain‒computer interfaces: overcoming biocompatibility challenges in implantable neural interfaces.Journal of nanobiotechnology · 2025Review
- A bioelectric router for adaptive isochronous neurostimulation enables multipolar bioelectric stimulation from a single source.Scientific reports · 2025Article
- Towards Precise Synthetic Neural Codes: High-dimensional Stimulation with Flexible Electrodes.Npj flexible electronics · 2025Article
- Visual Prostheses in the Era of Artificial Intelligence Technology.Eye and brain · 2025Review
- Inkjet-printed transparent electrodes: Design, characterization, and initial in vivo evaluation for brain stimulation.PloS one · 2025Article
- In vivo microelectrode arrays for neuroscience.Nature reviews. Methods primers · 2025Article
- Flexible Polymer Electrodes for Stable Prosthetic Visual Perception in Mice.Advanced healthcare materials · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Brain interfaces that can stimulate neurons, cause minimal damage, and work for a long time will be central for future neuroprosthetics. Here, the long-term performance of highly flexible, thin polyimide shanks with several small (<15 µm) electrodes during electrical microstimulation of the visual cortex, is reported. The electrodes exhibit a remarkable stability when several billions of electrical pulses are applied in vitro. When the devices are implanted in the primary visual cortex (area V1) of mice and the animals are trained to detect electrical microstimulation, it is found that the perceptual thresholds are 2-20 microamperes (µA), which is far below the maximal currents that the electrodes can withstand. The long-term functionality of the devices in vivo is excellent, with stable performance for up to more than a year and little damage to the brain tissue. These results demonstrate the potential of thin floating electrodes for the long-term restoration of lost sensory functions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.