Evidence map›Paper›PMID 38324098›Full record

ArticleInternational ophthalmology2024

Comparison of corneal biomechanical parameters in healthy corneas with symmetric and asymmetric bow-tie topographic pattern with inferior and superior steepening.

Mohammad-Reza Sedaghat, Hadi Ostadi-Moghaddam, Hamed Momeni-Moghaddam, Soulmaz Motaei, Cynthia J Roberts, Michael W Belin, Samin Oladi Abbas Abadi

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Article in International ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Mohammad-Reza SedaghatEye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Hadi Ostadi-MoghaddamRefractive Errors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Hamed Momeni-MoghaddamRehabilitation Sciences Research Center, Zahedan University of Medical Sciences, Kafami Str., Zahedan, Iran. hmomeni_opt@yahoo.com.
Soulmaz MotaeiDepartment of Optometry, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.
Cynthia J RobertsOphthalmology & Visual Sciences and Biomedical Engineering, The Ohio State University, Columbus, OH, USA.
Michael W BelinDepartment of Ophthalmology & Vision Science, University of Arizona, Tucson, AZ, USA.
Samin Oladi Abbas AbadiStudent Research Committee, Rehabilitation Sciences Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the corneal biomechanical parameters in healthy corneas with symmetric and asymmetric bow-tie topographic patterns.

methodsIn this cross-sectional study, 144 eyes were divided based on inferior-superior asymmetry value (I-S) into symmetric (zero I-S: - 0.50 to + 0.50 D) and asymmetric bow-tie topographic patterns with inferior (positive I-S: + 0.51 to + 1.4 D) or superior (negative I-S: - 2.5 to - 0.51 D) steepening. The biomechanical assessment was performed using Corvis ST and ocular response analyzer (ORA). A general linear model univariate analysis was used to compare the parameters, while the central corneal thickness, intraocular pressure, and age were considered covariates.

resultsOnly the peak distance (PD) at the highest concavity phase (P = 0.007) and tomographic biomechanical index (TBI, P = 0.001) showed statistically significant differences between the three groups. For TBI, this difference was statistically significant between the positive I-S group separately with the zero I-S group (P < 0.001), and with the negative I-S group (P = 0.022). For PD, the significant difference was between the negative I-S group separately with zero I-S (P = 0.019), and positive I-S groups (P = 0.018). There was a statistically significant correlation between the I-S value with PD (r = 0.281, P = 0.001) and TBI (r = 0.170, P = 0.044).

conclusionsMost corneal biomechanical parameters are not statistically significant compared to the zero I-S group. However, superior steepening is associated with a stiffer response based solely on the shorter PD values seen in this group, and the group with the inferior steepening shows the highest or more suspicious values based on TBI.

Indexed as

CorneaHealth StatusCross-Sectional StudiesHumansIntraocular PressureTonometry, OcularAsymmetry patternBow-tie patternCorneal biomechanicsCorneal topographyI–S value

Identifiers

PMID38324098

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.