Evidence map›Paper›PMID 38323821›Full record

ArticlemSystems2024

Machine learning analysis of RB-TnSeq fitness data predicts functional gene modules in

Andrew J Borchert, Alissa C Bleem, Hyun Gyu Lim, Kevin Rychel, Keven D Dooley, Zoe A Kellermyer, Tracy L Hodges, Bernhard O Palsson, Gregg T Beckham

Abstract read
In one paragraph

Article in mSystems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Barcoded mutant library enables high-throughput functional genomics in a filamentous fungus.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Multi-layered metabolic remodeling ofMetabolic engineering communications · 2026
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrew J Borchert *Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, Colorado, USA.ORCID 0000-0003-1435-3643
Alissa C Bleem *Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, Colorado, USA.ORCID 0000-0003-1586-2554
Hyun Gyu Lim *Department of Bioengineering, University of California San Diego, La Jolla, California, USA.ORCID 0000-0002-0469-2388
Kevin RychelDepartment of Bioengineering, University of California San Diego, La Jolla, California, USA.
Keven D DooleyRenewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, Colorado, USA.
Zoe A KellermyerRenewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, Colorado, USA.
Tracy L HodgesRenewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, Colorado, USA.
Bernhard O PalssonDepartment of Bioengineering, University of California San Diego, La Jolla, California, USA.ORCID 0000-0003-2357-6785
Gregg T BeckhamRenewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, Colorado, USA.ORCID 0000-0002-3480-212X

Funding

DOE Bioenergy Technologies Office DE-AC36-08GO28308DOE Biological and Environmental Research DE-AC02-05CH11231DOE Biological and Environmental Research DE-AC36-08GO28308
6 · The paper itself

Abstract

There is growing interest in engineering IMPORTANCE: This study demonstrates a rapid, automated approach for elucidating functional modules within complex genetic networks. While

Indexed as

Pseudomonas putidaGene Regulatory NetworksGenomicsamino acid metabolismaromatic catabolismfunctional genomicsindependent component analysismachine learningPseudomonas putidaRB-TnSeqtransposon insertion sequencing

Identifiers

PMID38323821
PMCPMC10949508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.