Evidence map›Paper›PMID 38323810›Full record

ArticleJournal of virology2024

Single-cell RNA-seq revealed heterogeneous responses and functional differentiation of hemocytes against white spot syndrome virus infection in

Chuang Cui, Xiaoqian Tang, Jing Xing, Xiuzhen Sheng, Heng Chi, Wenbin Zhan

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  9. The pathogenesis ofParasitology · 2025
    Review
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  12. The NamBio · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Chuang CuiLaboratory of Pathology and Immunology of Aquatic Animals, KLMME, Ocean University of China, Qingdao, China.
Xiaoqian TangLaboratory of Pathology and Immunology of Aquatic Animals, KLMME, Ocean University of China, Qingdao, China.ORCID 0000-0001-5810-5655
Jing XingLaboratory of Pathology and Immunology of Aquatic Animals, KLMME, Ocean University of China, Qingdao, China.ORCID 0000-0003-0096-3061
Xiuzhen ShengLaboratory of Pathology and Immunology of Aquatic Animals, KLMME, Ocean University of China, Qingdao, China.
Heng ChiLaboratory of Pathology and Immunology of Aquatic Animals, KLMME, Ocean University of China, Qingdao, China.
Wenbin ZhanLaboratory of Pathology and Immunology of Aquatic Animals, KLMME, Ocean University of China, Qingdao, China.ORCID 0000-0002-5672-5137
Qingdao National Laboratory for Marine Science and Technology · CNOcean University of China · CN

Funding

MOST | National Key Research and Development Program of China (NKPs) 2019YFD0900101MOST | National Key Research and Development Program of China (NKPs) 2023YDF2400701Qingdao National Laboratory for Marine Science and Technology (QNLM) QNLM2016ORP0307Taishan Scholar Foundation of Shandong Province ()
6 · The paper itself

Abstract

Shrimp hemocytes are the vital immune cells participating in innate immune response to defend against viruses. However, the lack of specific molecular markers for shrimp hemocyte hindered the insightful understanding of their functional clusters and differential roles in combating microbial infections. In this study, we used single-cell RNA sequencing to map the transcriptomic landscape of hemocytes from the white spot syndrome virus (WSSV)-infected IMPORTANCE: Current knowledge of shrimp hemocyte classification mainly comes from morphology, which hinder in-depth characterization of cell lineage development, functional differentiation, and different immune response of hemocyte types during pathogenic infections. Here, single-cell RNA sequencing was used for mapping hemocytes during white spot syndrome virus (WSSV) infection in

Indexed as

Arthropod ProteinsHemocytesHost Microbial InteractionsPenaeidaeRNA-SeqSingle-Cell Gene Expression AnalysisWhite spot syndrome virus 1AnimalsCell DifferentiationGene Expression RegulationArthropod Proteinshemocyte clustersimmune responseLitopenaeus vannameisingle-cell RNA-seqWSSV

Identifiers

PMID38323810
PMCPMC10949519
OpenAlexW4391600467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.