Evidence map›Paper›PMID 38323304›Full record

ArticleGreen chemistry : an international journal and green chemistry resource : GC2024

Nature stays natural: two novel chemo-enzymatic one-pot cascades for the synthesis of fragrance and flavor aldehydes.

Stefan Giparakis, Margit Winkler, Florian Rudroff

Abstract read
In one paragraph

Article in Green chemistry : an international journal and green chemistry resource : GC, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stefan GiparakisTU Wien, Institute of Applied Synthetic Chemistry Getreidemarkt 9 163-OC 1060 Vienna Austria florian.rudroff@tuwien.ac.at.
Margit WinklerTU-Graz, Institut für Molekulare Biotechnologie Petersgasse 14 8010 Graz Austria.ORCID https://orcid.org/0000-0002-0754-9704
Florian RudroffTU Wien, Institute of Applied Synthetic Chemistry Getreidemarkt 9 163-OC 1060 Vienna Austria florian.rudroff@tuwien.ac.at.ORCID https://orcid.org/0000-0002-6680-8200

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel synthetic strategies for the production of high-value chemicals based on the 12 principles of green chemistry are highly desired. Herein, we present a proof of concept for two novel chemo-enzymatic one-pot cascades allowing for the production of valuable fragrance and flavor aldehydes. We utilized renewable phenylpropenes, such as eugenol from cloves or estragole from estragon, as starting materials. For the first strategy, Pd-catalyzed isomerization of the allylic double bond and subsequent enzyme-mediated (aromatic dioxygenase, ADO) alkene cleavage were performed to obtain the desired aldehydes. In the second route, the double bond was oxidized to the corresponding ketone

Identifiers

PMID38323304
PMCPMC10840651

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.