ArticleBehavioural neurology2024
Abnormal Amygdala Subregion Functional Connectivity in Patients with Crohn's Disease with or without Anxiety and Depression.
Article in Behavioural neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Disrupted Functional Network Organization in Crohn's Disease: Interoceptive Alterations Linked to Anxiety.CNS neuroscience & therapeutics · 2026Article
- Across Barriers: Blood-Brain and Gut Barrier Signaling in Psychiatric Disorders.Journal of neurochemistry · 2025Review
- Shared neurobiological changes in individuals with Crohn's disease and major depressive disorder.Communications medicine · 2025Article
- A Heavy Feeling in the Stomach: Neural Correlates of Anxiety in Crohn's Disease.Neurogastroenterology and motility · 2025Article
- Current approaches to studying human resting-state function in inflammatory bowel disease.Journal of the Canadian Association of Gastroenterology · 2025Article
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Authors and funding
8 authors.
Funding
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Abstract
Objective: The aim of this study was to explore the resting-state functional connectivity (rsFC) of amygdala subregions in healthy controls (HCs) and in patients with Crohn's disease (CD) both with and without anxiety or depression. Materials and Methods: A total of 33 patients with CD and with anxiety or depression (CDad group), 31 patients with CD but without anxiety or depression (CDnad group), and 29 age-, sex-, and education level-matched HCs underwent functional magnetic resonance imaging. rsFC analysis was used to analyze the FC between the amygdala subregions and other areas of the brain. Results: Compared with the HC group, the CDad group demonstrated decreased rsFC between the right laterobasal subregion and the left hippocampus ( Conclusions: There are significant FC changes in the amygdala subregions in patients with CD. These changes may be related to the disease itself or to the symptoms of anxiety and depression.
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