ArticleFrontiers in endocrinology2024
Comparison of seven surrogate insulin resistance indexes for prediction of incident coronary heart disease risk: a 10-year prospective cohort study.
Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
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34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Associations of triglyceride-glucose-related composite obesity indices with cardiovascular diseases and mortality: a systematic review and meta-analysis.Cardiovascular diabetology · 2026Pooled it
- Does diabetes status modify the association between the triglyceride-glucose index and major adverse cardiovascular events in patients with coronary heart disease? A systematic review and meta-analysis of longitudinal cohort studies.Cardiovascular diabetology · 2025Pooled it
- Triglyceride-glucose-body mass index and the incidence of cardiovascular diseases: a meta-analysis of cohort studies.Cardiovascular diabetology · 2025Pooled it
- Optimizing early triage for subclinical cardiovascular-kidney-metabolic syndrome: longitudinal associations, incremental value, and clinical utility of nine insulin resistance surrogates.Cardiovascular diabetology · 2026Article
- Long-term metabolic-adiposity burden and cardiovascular risk: the cumTyG-WHtR in Chinese adults.BMC cardiovascular disorders · 2026Article
- Comparative evaluation of nine insulin resistance indices for 10-year coronary artery disease risk prediction in non-diabetic adults.Scientific reports · 2026Article
- Association between the triglyceride glucose index:Chinese visceral adiposity index (TyG-CVAI) and new-onset cardiovascular disease in middle-aged and older adults-insights from the China Health and Retirement Longitudinal Study (CHARLS).Cardiovascular diabetology · 2026Article
- Development and validation of a nomogram for predicting peripheral atherosclerosis in early-stage type 2 diabetic kidney disease: a retrospective hospital-based study.Frontiers in endocrinology · 2026Article
- The effects of Traditional Chinese Medicine on cardiac function after percutaneous coronary intervention: a meta-analysis and systematic review.Frontiers in cardiovascular medicine · 2026Review
- Article
- Associations of triglyceride-glucose-related indices and cardiovascular health with retinal arteriosclerosis: a cross-sectional study.Frontiers in public health · 2026Article
- Article
- Comparison of nine insulin resistance surrogates for predicting cardiovascular disease: a cohort study.Diabetology & metabolic syndrome · 2025Article
- [Predictive value of a Chinese visceral adiposity index for metabolic associated fatty liver disease].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025Article
- Comparison of six surrogate insulin resistance indices for predicting the accumulation of pericardial fat on noncontrast computed tomography.Quantitative imaging in medicine and surgery · 2025Article
- Triglyceride glucose-weight-adjusted waist index as a cardiovascular mortality predictor: incremental value beyond the establishment of TyG-related indices.Cardiovascular diabetology · 2025Article
- The Correlation Between Triglyceride-Glucose-Body Mass Index, and the Risk of Silent Myocardial Infarction: Construction of a Predictive Model.Reviews in cardiovascular medicine · 2025Article
- Early Cardiovascular and Metabolic Benefits of rhGH Therapy in Adult Patients with Severe Growth Hormone Deficiency: Impact on Oxidative Stress Parameters.International journal of molecular sciences · 2025Article
- Association between insulin resistance and multiple chronic diseases: a cross-sectional study from CHARLS.Journal of health, population, and nutrition · 2025Article
- Can cardiovascular health and its modifiable healthy lifestyle offset the increased risk of all-cause and cardiovascular deaths associated with insulin resistance?Cardiovascular diabetology · 2025Article
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10 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Background: There were seven novel and easily accessed insulin resistance (IR) surrogates established, including the Chinese visceral adiposity index (CVAI), the visceral adiposity index (VAI), lipid accumulation product (LAP), triglyceride glucose (TyG) index, TyG-body mass index (TyG-BMI), TyG-waist circumference (TyG-WC) and TyG-waist to height ratio (TyG-WHtR). We aimed to explore the association between the seven IR surrogates and incident coronary heart disease (CHD), and to compare their predictive powers among Chinese population. Methods: This is a 10-year prospective cohort study conducted in China including 6393 participants without cardiovascular disease (CVD) at baseline. We developed Cox regression analyses to examine the association of IR surrogates with CHD (hazard ratio [HR], 95% confidence intervals [CI]). Moreover, the receiver operating characteristic (ROC) curve was performed to compare the predictive values of these indexes for incident CHD by the areas under the ROC curve (AUC). Results: During a median follow-up period of 10.25 years, 246 individuals newly developed CHD. Significant associations of the IR surrogates (excepted for VAI) with incident CHD were found in our study after fully adjustment, and the fifth quintile HRs (95% CIs) for incident CHD were respectively 2.055(1.216-3.473), 1.446(0.948-2.205), 1.753(1.099-2.795), 2.013(1.214-3.339), 3.169(1.926-5.214), 2.275(1.391-3.719) and 2.309(1.419-3.759) for CVAI, VAI, LAP, TyG, TyG-BMI, TyG-WC and TyG-WHtR, compared with quintile 1. Furthermore, CVAI showed maximum predictive capacity for CHD among these seven IR surrogates with the largest AUC: 0.632(0.597,0.667). Conclusion: The seven IR surrogates (excepted for VAI) were independently associated with higher prevalence of CHD, among which CVAI is the most powerful predictor for CHD incidence in Chinese populations.
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