ArticleiScience2024
Evaluation of cerebrovascular reactivity in moyamoya disease using oxygen-dependent magnetic resonance imaging.
Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Default mode network and visual network responsiveness to transcutaneous auricular vagus nerve stimulation predict its variable efficacy in primary insomnia disorder.Frontiers in neurology · 2025Trial
- Calibration-Free Estimation of Cerebrovascular Reactivity From Resting-State BOLD fMRI Using Reconstructed Respiratory Fluctuations.Magnetic resonance in medicine · 2026Article
- Resting-state BOLD fMRI-derived cerebrovascular reactivity for detecting crossed cerebellar diaschisis.Neuroradiology · 2026Article
- Assessment of cerebrovascular reserve using acetazolamide brain perfusion SPECT in Moyamoya disease.Asia Oceania journal of nuclear medicine & biology · 2026Article
- Advances in cerebrovascular reserve function assessment for moyamoya disease.BMJ neurology open · 2026Review
- Disrupted resting-state interhemispheric functional connectivity in patients with first-episode moyamoya disease.Scientific reports · 2025Article
- Vascular architecture characters and risk factors analysis of unstable moyamoya disease.Frontiers in neurology · 2024Article
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Authors and funding
10 authors.
Funding
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Abstract
Moyamoya disease (MMD) is a rare cerebrovascular disorder marked by progressive stenosis of the internal carotid arteries. Assessing cerebral hemodynamics, specifically cerebrovascular reactivity (CVR), is vital for MMD management and prognosis. In this study, fMRI was performed in a prospective cohort of 47 patients with MMD and 32 healthy controls to investigate its utility in evaluating CVR and to explore the influence of cerebral posterior circulation compensation on CVR in MMD. The regions where the CVR values of participants with MMD were lower than those of healthy controls were primarily concentrated in the frontal, parietal, and temporal lobes (p < 0.05). In certain regions mainly supplied by posterior circulation, the CVR values of compensatory-normal subgroup tended to exceed those of compensatory-poor subgroup. fMRI can detect a significant decrease in CVR values in patients with MMD compared to healthy controls. Compensation for the posterior cerebral circulation may affect cerebrovascular reactivity.
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