ArticleThe Lancet regional health. Western Pacific2024
Failure to thrive in pediatric patients with congenital heart disease: a cross-sectional study of 13,256 patients.
Article in The Lancet regional health. Western Pacific, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Achieving Protein Requirements Through Oral Feeding in Children with Congenital Heart Disease: A Narrative Review.Children (Basel, Switzerland) · 2026Review
- Charitable funding of congenital heart surgery in China: A cost-effectiveness analysis from the National Center for Cardiovascular Diseases.JTCVS open · 2026Article
- An interpretable machine learning model for preoperative risk stratification in paediatric congenital heart disease surgery: a retrospective cohort study.Journal of cardiothoracic surgery · 2026Article
- Relationship Between Central Venous Pressure, Cardiac Index, and Renal Function in Pediatric Heart Failure: a Pediatric Heart Transplant Society Study.Pediatric cardiology · 2026Article
- Anemia in children with congenital heart disease and its association with postoperative prognosis.Italian journal of pediatrics · 2026Article
- Preoperative echocardiographic predictors of mitral valve repair failure in children.European journal of pediatrics · 2026Article
- Severity of Congenital Heart Defects Affects Long-Term Somatic Development.Pediatric cardiology · 2026Article
- Can development alone save lives? trends and forecasts of congenital heart anomalies-attributable premature mortality in ASEAN.Frontiers in cardiovascular medicine · 2026Article
- Impact of anatomic complexity of congenital heart disease on growth retardation: a large retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- Disease and Economic Burden of Intellectual Developmental Disability Attributable to Congenital Heart Disease, 1990-2021.Global heart · 2026Article
- Screening modality matters: heterogeneous nutritional status, disease complexity in children with congenital heart disease detected through active versus passive surveillance.Frontiers in nutrition · 2026Article
- Comparative assessment of nutritional status in unoperated children with Congenital Heart Defects: Insights from a tertiary pediatric cardiac center in India.PLOS global public health · 2025Article
- Evaluating Malnutrition Practices and Mother's Education on Children Failure to Thrive Symptoms Using Entropy-Weight and TOPSIS Method.Children (Basel, Switzerland) · 2024Article
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9 authors.
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Abstract
Background: The prevalence and risk factors for failure to thrive (FTT) in pediatric patients with congenital heart disease (CHD) remain ambiguous. We aimed to investigate the prevalence, growth profiles, risk factors, and vulnerable subtypes of CHD associated with FTT in pediatric patients with CHD. Methods: This was a cross-sectional study based on Chinese Database for Congenital Heart Surgery. FTT was defined as either stunting or underweight (height or weight standard deviation score <-2), and they were standardized by references of normal Chinese population. Risk factors was determined with logistic regression model, and growth profiles were delineated in each subgroup. Findings: A total of 13,256 CHD patients were included in this study, with 3994 patients of mild CHD, 7195 patients of moderate CHD and 2067 patients of complex CHD. The prevalence of stunting, underweight and FTT was 24%, 29.3% and 36.9%, respectively. Preoperative anaemia, left ventricle systolic dysfunction, younger age, more complex CHD types, lower birth weight and genetic syndrome were found to be the risk factors for FTT in CHD patients. Interrupted aortic arch was revealed to be the most severe group associated with FTT. Interpretation: FTT is ubiquitous in patients with CHD and exacerbated in high-risk subgroups. Our findings hinted the necessity of early identification and intervention for FTT in patients with CHD during daily practice of pediatrics, as it has the potential to improve outcomes and enhance their quality of life. Furthermore, we advocate for the initiation of prospective research with longitudinal data to comprehensively investigate the association between FTT and CHD across the lifespan. Funding: This study was supported by National High Level Hospital Research Funding (2022-GSP-GG-19), Capital Health Research and Development of Special Fund (2022-1-4032) and National Key R&D Program of China (2022YFC3600202 and 2022YFC3600203).
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