ArticleKidney diseases (Basel, Switzerland)2024
Association between the Triglyceride Glucose Index and All-Cause Mortality in Critically Ill Patients with Acute Kidney Injury.
Article in Kidney diseases (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between triglyceride glucose index and risk of acute kidney injury in critically ill patients: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Association of triglyceride glucose index with mortality in critically ill patients with atherosclerotic cardiovascular disease: analysis of the MIMIC-IV database.European journal of medical research · 2026Article
- The triglyceride-glucose index in chronic kidney disease: a narrative review.Frontiers in nutrition · 2026Review
- Triglyceride-glucose index and triglyceride-to-high-density lipoprotein cholesterol ratio as novel predictors of acute kidney injury: an analysis of the UK biobank.Renal failure · 2025Article
- Elevated triglyceride-glucose index and acute kidney injury risk in critical atrial fibrillation: an analysis from MIMIC-IV.BMC cardiovascular disorders · 2025Article
- Association between the triglyceride glucose index and long-term outcomes in patients with acute coronary syndrome and chronic kidney disease.Diabetology & metabolic syndrome · 2025Article
- Association of the triglyceride glucose index with acute renal failure in diabetes mellitus: a cross-sectional study based on participants from the MIMIC-iv database.Acta diabetologica · 2025Article
- Article
- Association between triglyceride-glucose index and risk of acute kidney injury in patients with aneurysmal subarachnoid hemorrhage.Acta neurochirurgica · 2025Article
- Associations of the triglyceride-glucose index with mortality mediated by blood urea nitrogen among critically ill patients: a cohort study.Scientific reports · 2025Article
- Association between the triglyceride-glucose index and acute kidney injury in patients undergoing percutaneous coronary: a retrospective analysis of the MIMIC-IV database.Diabetology & metabolic syndrome · 2025Article
- Association between the triglyceride-glucose index and the risk of acute kidney injury in critically ill patients with acute pancreatitis: a retrospective study.Journal of intensive care · 2025Article
- Dynamic trajectories of the triglyceride-glucose index link to all-cause hospital mortality in patients with hypertension and kidney failure: a multicenter study.Frontiers in endocrinology · 2025Article
- Associations between triglyceride-glucose indices and delirium risk in critically ill patients with acute kidney injury: a retrospective study.Frontiers in endocrinology · 2025Article
- Emergency risk stratification using the TyG index: a multi-center cohort study on nonlinear association with 28-day mortality among critically ill patients transferred from the ED to the ICU.Frontiers in medicine · 2025Article
- Antidiabetic and lipid-lowering therapy modify the association between triglyceride-glucose index and acute kidney injury in critically ill patients with coronary artery disease.Frontiers in endocrinology · 2025Article
- The Association Between Diabetic Nephropathy and Triglyceride/Glucose Index and Triglyceride/High-Density Lipoprotein Cholesterol Ratio in Patients with Type 2 Diabetes Mellitus.Journal of clinical medicine · 2024Article
- Association between the triglyceride glucose index and the risk of acute kidney injury in critically ill patients with hypertension: analysis of the MIMIC-IV database.Frontiers in endocrinology · 2024Article
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5 authors.
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Abstract
Introduction: The triglyceride glucose (TyG) index is a reliable alternative biomarker of insulin resistance, but the association between the TyG index and acute kidney injury (AKI) in critically ill patients remains unclear. Methods: The data for the study were extracted from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. Cox regression and restricted cubic spline (RCS) analysis were performed to analyze the association between the TyG index and all-cause mortality. Besides, Cox regression was carried out in subgroups of age, gender, BMI, diabetes history, and dialysis status. Results: A total of 7,508 critically ill participants with AKI from the MIMIC-IV database were included in this study, with 3,688 (49.12%) participants failed to survive. In Cox regression, after confounder adjustment, patients with a higher TyG index had a higher risk of all-cause mortality (HR = 1.845, 95% CI = 1.49-2.285, Conclusion: Overall, a higher TyG index is associated with a higher risk of all-cause mortality in critically ill AKI. Interestingly, the relationship in the dialysis subgroup follows a "U"-shaped curve, indicating the importance of proper clinical blood glucose and lipid management in this particular population.
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