ReviewMediastinum (Hong Kong, China)2024
A clinical review of spontaneous pneumomediastinum.
Review in Mediastinum (Hong Kong, China), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Article
- Optimising Autologous Breast Reconstruction: Pneumothorax and Pneumomediastinum-A Literature Review and First Reported Case of Pneumomediastinum Following Bilateral DIEP Flap Reconstruction.Journal of personalized medicine · 2026Review
- Swallowing‑induced spontaneous pneumomediastinum after ingestion of a large, unchewed food bolus in a young adult: a case report.International journal of emergency medicine · 2026Article
- A Crunch That Spoke: An Atypical Presentation of Spontaneous Pneumomediastinum in an Elderly Male.Cureus · 2026Article
- Article
- Zenker's diverticulum in the era of third-space endoscopy: innovations, challenges, and adverse event management.iGIE : innovation, investigation and insights · 2026Review
- Extensive Spontaneous Pneumomediastinum With Suspected Recurrence in a Young Woman: A Case of Hamman Syndrome.Cureus · 2026Article
- Clinical characteristics of 40 patients with spontaneous pneumomediastinum: a retrospective study and literature review.Journal of cardiothoracic surgery · 2026Review
- Spontaneous Pneumomediastinum Following Intense Gym Exercise in a Healthy Young Male: A Case Report.Cureus · 2026Article
- Spontaneous Pneumomediastinum Following Severe Vomiting in a Previously Healthy Young Adult.Cureus · 2026Article
- Spontaneous Pneumomediastinum and Cannabinoid Hyperemesis Syndrome: A Case Report and Literature Review.Cureus · 2026Article
- Spontaneous pneumomediastinum and subcutaneous emphysema during acute exacerbation of idiopathic pulmonary fibrosis: a case report.Respiratory medicine case reports · 2026Article
- Spontaneous Pneumomediastinum in COVID-19 and Myasthenic-like Symptom Complications in Two Relatives: A Coincidence or Spike Toxicity with Thymic Response in Predisposed Individuals? Two Clinical Cases with a Comprehensive Literature Review.Journal of clinical medicine · 2025Article
- Article
- Unexpected Pneumomediastinum in Crohn's Disease: Implications and Case Analysis.The American journal of case reports · 2025Article
- Subcutaneous Emphysema and Pneumomediastinum Triggered by Nasotracheal Intubation: A Case Report.Cureus · 2025Article
- Pneumomediastinum in Acute Asthma Exacerbation.Cureus · 2025Article
- Case Report: Spontaneous Pneumomediastinum and Pneumothorax Complicating Severe Ketoacidosis-An Unexpected Presentation.Reports (MDPI) · 2025Article
- Resolution is not the end: The Macklin effect after chest tube removal in a trauma patient with aging and comorbidities: a case report.Journal of trauma and injury · 2025Article
- Spontaneous Pneumomediastinum: A Narrative Review Offering a New Perspective on Its Definition and Classification.Cureus · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary spontaneous pneumomediastinum is a rare, often benign and self-limited condition defined by air within the mediastinum. However, correctly distinguishing primary spontaneous pneumomediastinum from secondary causes, especially esophageal perforation, remains a diagnostic challenge. There is significant debate regarding the balance of completing a thorough but not overly invasive and costly diagnostic workup. This clinical review aims to gather the limited data regarding spontaneous pneumomediastinum management from case series and retrospective cohort studies, and presents an evaluation algorithm and treatment plan stratified by clinical history. Understanding specifically if the patient presents with coughing versus forceful vomiting is critical to help elucidate the etiology and guide management of pneumomediastinum. Patients who present with forceful vomiting or retching should be considered with higher degree of suspicion for secondary causes of pneumomediastinum, specifically esophageal perforation. However, especially in children, aggressive diagnostic workup is not warranted in every case. After ruling out other etiologies of pneumomediastinum, spontaneous pneumomediastinum can be commonly treated with symptomatic management without the aggressive use of antibiotics or diet restriction. Hospital length of stay may also be minimized on a case-by-case basis. Overall, recurrence of spontaneous pneumomediastinum is rare and outpatient follow up may be safely limited to those at highest risk of recurrence.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.