ArticleJournal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience2022
Using Zebrafish Embryos to Study Pharmacological Effects on Neural Development in Hands-On Neurobiology Laboratory Activities.
Article in Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Reimagining pharmacology education.Pharmacological reviews · 2026Review
- The New and Even Better Normal.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Undergraduate neurobiology courses cover neural development as a major theme but there are few labs to provide hands-on experience with these topics. Here we share a 3-week set of lab activities using zebrafish embryos that allow students to see the direct effect of drug exposure on physical and emotional development. In these labs, student expose new embryos (Lab 1) to the environmental toxin lithium chloride, which inhibits anterior development and produces an eyeless phenotype in fixed larvae (Lab 2), and to psychiatric medications fluoxetine and quetiapine, which alter anxiety-like behavior measured live in grown juveniles (Lab 3). Lab worksheets ask students to investigate the signaling pathways affected by these drugs and how they might affect neural development in different ways. Student opinion surveys suggest these lab activities were successful in both providing hands-on work with zebrafish as a model organism for neural development and better understanding of how drugs can impact development of the nervous system.
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Registered trials
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