Evidence map›Paper›PMID 38321938›Full record

ReviewPediatrics2024

Postacute Sequelae of SARS-CoV-2 in Children.

Suchitra Rao, Rachel S Gross, Sindhu Mohandas, Cheryl R Stein, Abigail Case, Benard Dreyer, Nathan M Pajor, H Timothy Bunnell, David Warburton, Elizabeth Berg and 12 more

Abstract readReview
In one paragraph

Review in Pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Post-MIS-C cardiovascular outcomes: a systematic review.European journal of pediatrics · 2026
    Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Review
  7. Article
  8. Observational
  9. Article
  10. Review
  11. Review
  12. Observational
  13. Review
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Review
  19. Unique nasal cell states induced by common pediatric respiratory viruses.bioRxiv : the preprint server for biology · 2026
    Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Suchitra RaoDepartment of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colorado.
Rachel S GrossDepartments of Pediatrics.
Sindhu MohandasDivision of Infectious Diseases.
Cheryl R SteinChild and Adolescent Psychiatry, New York University Grossman School of Medicine, New York, New York.
Abigail CaseDepartment of Pediatrics and Rehabilitation Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Benard DreyerDepartment of Pediatrics and Radiology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California.
Nathan M PajorDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio.
H Timothy BunnellBiomedical Research Informatics Center, Nemours Children's Health, Nemours Children's Hospital, Delaware, Wilmington, Delaware.
David WarburtonDepartment of Pediatrics and Radiology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California.
Elizabeth BergDepartment of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons, New York, New York.
Jonathan B OverdevestDepartment of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons, New York, New York.
Mark GorelikDepartment of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons, New York, New York.
Joshua MilnerDepartment of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons, New York, New York.
Sejal SaxenaDepartment of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons, New York, New York.
Ravi JhaveriDivision of Infectious Diseases, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
John C WoodDepartment of Pediatrics and Radiology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California.
Kyung E RheeDepartment of Pediatrics, University of California, San Diego, School of Medicine, San Diego, California.
Rebecca LettsPopulation Health, NYU Grossman School of Medicine, New York, New York.
Christine MaughanPopulation Health, NYU Grossman School of Medicine, New York, New York.
Nick GuthePopulation Health, NYU Grossman School of Medicine, New York, New York.
Leah Castro-BaucomPopulation Health, NYU Grossman School of Medicine, New York, New York.
Melissa S StockwellDepartment of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons, New York, New York.

Funding

OTA-21-015A Post-Acute Sequelae of SARS-CoV-2 Infection Initiative: NYU Langone Health Clinical Science Core, Data Resource Core, and PASC Biorepository CoreOT2HL161847 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GROSS, RACHEL SHARON, HORWITZ, LEORA · 2021 to 2025
$651.0M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Neurocognitive & neuropsychiatric impact of chemosensory alterations: Implications of olfactory dysfunction in COVID-19K23DC019678 · NIDCD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI OVERDEVEST, JONATHAN B · 2021 to 2025
$893k
NHLBI NIH HHS OT2 HL161847NIDCD NIH HHS K23 DC019678NIDDK NIH HHS P30 DK111022
6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) pandemic has caused significant medical, social, and economic impacts globally, both in the short and long term. Although most individuals recover within a few days or weeks from an acute infection, some experience longer lasting effects. Data regarding the postacute sequelae of severe acute respiratory syndrome coronavirus 2 infection (PASC) in children, or long COVID, are only just emerging in the literature. These symptoms and conditions may reflect persistent symptoms from acute infection (eg, cough, headaches, fatigue, and loss of taste and smell), new symptoms like dizziness, or exacerbation of underlying conditions. Children may develop conditions de novo, including postural orthostatic tachycardia syndrome, myalgic encephalomyelitis/chronic fatigue syndrome, autoimmune conditions and multisystem inflammatory syndrome in children. This state-of-the-art narrative review provides a summary of our current knowledge about PASC in children, including prevalence, epidemiology, risk factors, clinical characteristics, underlying mechanisms, and functional outcomes, as well as a conceptual framework for PASC based on the current National Institutes of Health definition. We highlight the pediatric components of the National Institutes of Health-funded Researching COVID to Enhance Recovery Initiative, which seeks to characterize the natural history, mechanisms, and long-term health effects of PASC in children and young adults to inform future treatment and prevention efforts. These initiatives include electronic health record cohorts, which offer rapid assessments at scale with geographical and demographic diversity, as well as longitudinal prospective observational cohorts, to estimate disease burden, illness trajectory, pathobiology, and clinical manifestations and outcomes.

Indexed as

Autoimmune DiseasesCOVID-19Systemic Inflammatory Response SyndromeChildDisease ProgressionHumansObservational Studies as TopicPost-Acute COVID-19 SyndromeSARS-CoV-2United States

Identifiers

PMID38321938
PMCPMC10904902

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.