Evidence map›Paper›PMID 38321617›Full record

ArticleThe International journal of eating disorders2024

Overvaluation of shape/weight at posttreatment predicts relapse at 12-month follow-up after successful behaviorally-based treatment of binge-eating disorder.

Carlos M Grilo, Valentina Ivezaj, Ralitza Gueorguieva

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in The International journal of eating disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00829283 (Treatment of Obesity and Binge Eating), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00829283 nacompletednot on this map

Treatment of Obesity and Binge Eating: Behavioral Weight Loss Versus Stepped Care

TypeinterventionalSponsorYale UniversityRan2008 to 2013Enrolled191ConditionsObesity, Binge EatingArmsBehavioral Weight Loss, Behavioral Weight Loss + Guided self-help Cognitive-behavioral Therapy, Placebo, Sibutramine/Orlistat
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
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  4. Visible yet Invisible: embodied meanings of weight stigma among women with binge eating disorder and higher weight.International journal of qualitative studies on health and well-being · 2025
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  7. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Carlos M GriloDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0003-0245-3444
Valentina IvezajDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0001-8760-8040
Ralitza GueorguievaDepartment of Biostatistics, Yale School of Public Health, New Haven, Connecticut, USA.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Treatment of Obesity and Binge Eating: Behavioral weight Loss versus Stepped CareR01DK049587 · NIDDK · YALE UNIVERSITY · PI GRILO, CARLOS M · 2002 to 2020
$8.5M
Efficacy and Mechanisms of Naltrexone+Bupropion for Binge Eating DisorderR01DK112771 · NIDDK · YALE UNIVERSITY · PI GRILO, CARLOS M, MCKEE, SHERRY ANN · 2017 to 2021
$3.6M
Cognitive-Behavioral and Pharmacologic Treatment of Binge Eating DisorderR01DK114075 · NIDDK · YALE UNIVERSITY · PI GRILO, CARLOS M · 2018 to 2022
$3.6M
Neurocognitive fMRI Mechanisms of CBT and Lisdexamfetamine Outcomes in Obesity and BEDR01DK121551 · NIDDK · YALE UNIVERSITY · PI GRILO, CARLOS M, POTENZA, MARC N · 2019 to 2023
$1.8M
NCATS NIH HHS UL1 TR001863NIDDK NIH HHS R01 DK049587NIDDK NIH HHS R01 DK112771NIDDK NIH HHS R01 DK114075NIDDK NIH HHS R01 DK121551NIDDK NIH HHS R01 DK49587
6 · The paper itself

Abstract

objectiveTo test whether overvaluation of shape/weight at the end of treatment prospectively predicts relapse at 12-month follow-up in patients with binge-eating disorder (BED).

methodParticipants were 129 patients with BED who achieved abstinence from binge eating after 6 months of behaviorally-based weight-loss treatments in a clinical trial. Independent assessments conducted at posttreatment and at 12-month follow-up included the Eating Disorder Examination interview, the Beck Depression Inventory, and weight measurements.

resultsOf the 129 participants who attained abstinence from binge-eating at posttreatment, 46 (36%) were categorized with clinical overvaluation and 83 (64%) with subclinical overvaluation; 115 (89%) were re-assessed at 12-month follow-up. Participants with overvaluation at posttreatment were significantly more likely than those without to relapse at 12-months to non-abstinence from binge eating (54% vs. 28%) and to diagnosis-level binge-eating frequency of once weekly or greater (31% vs. 13%). Overvaluation at posttreatment predicted significantly higher eating-disorder psychopathology and depression scores at 12-month follow-up but were unrelated to weight and weight changes. Treatment groups did not have main or interaction effects; posttreatment overvaluation effects were observed regardless of treatment and of covarying for posttreatment value of dependent variables.

conclusionsOur findings suggest that overvaluation of shape/weight at the end of treatment predicts relapse and heightened eating-disorder psychopathology and depression scores 1 year later in patients who achieved abstinence from binge eating with behaviorally-based treatments. Overvaluation of shape/weight has significant clinical implications and warrants consideration as a diagnostic specifier for BED as it provides important prospective prognostic information. PUBLIC SIGNIFICANCE: Although effective treatments are available for binge-eating disorder, relapse following successful treatments is not uncommon. Almost nothing is known about what predicts relapse following treatments for binge-eating disorder. Our study found that overvaluation of shape/weight (i.e., body image concerns that overly impact self-worth) at posttreatment prospectively predicted relapse and higher eating-disorder psychopathology and depression 1 year later in patients who achieved binge-eating abstinence with behaviorally based treatments. CLINICALTRIALS: gov registration: NCT00829283. (Treatment of obesity and binge eating: Behavioral weight loss vs. stepped care.).

Indexed as

Binge-Eating DisorderBody ImageBody WeightRecurrenceAdultBehavior TherapyFemaleFollow-Up StudiesHumansMaleMiddle AgedTreatment Outcomebehavior therapybinge eatingbody imageeating disordersobesityrelapse

Identifiers

PMID38321617
PMCPMC11093697
OpenAlexW4391605453

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.