Evidence map›Paper›PMID 38321380›Full record

SynthesisBMC neurology2024

The prevalence and risk factors for phantom limb pain: a cross-sectional survey.

Katleho Limakatso, F Ndhlovu, A Usenbo, S Rayamajhi, C Kloppers, R Parker

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07393139 (Early Postoperative Pain and Functional Recovery Following a Limb Amputation), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
9.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07393139 recruitingnot on this mapstarted 2026, after this paper: background citation

Early Postoperative Pain and Functional Recovery Following a Limb Amputation: a Retrospective Observational Study.

TypeobservationalSponsorIstituto Ortopedico RizzoliRan2026 to 2026Enrolled150ConditionsAmputation, Surgical, Pain Management, RehabilitationArmsPain assessment
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Observational
  4. Article
  5. Article
  6. Phantom Limb Pain Assessment Tools: A Literature Review Exploring Strengths and Limitations.Archives of rehabilitation research and clinical translation · 2025
    Review
  7. In Reply.Deutsches Arzteblatt international · 2025
    Article
  8. Article
  9. Article
  10. Motor cortex stimulation for phantom limb pain treatment.Surgical neurology international · 2025
    Article
  11. Epidemiology and risk factors for phantom limb pain.Frontiers in pain research (Lausanne, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Katleho LimakatsoPain Management Unit, Department of Anaesthesia and Perioperative Medicine, Neuroscience Institute, University of Cape Town, Cape Town, South Africa.
F NdhlovuDepartment of Anaesthesiology, Nelson Mandela Academic Hospital, Mthatha, South Africa.
A UsenboDepartment of Anaesthesiology, Nelson Mandela Academic Hospital, Mthatha, South Africa.
S RayamajhiDepartment of Acute Care Surgery, Groote Schuur Hospital, Cape Town, South Africa.
C KloppersDepartment of Acute Care Surgery, Groote Schuur Hospital, Cape Town, South Africa.
R ParkerPain Management Unit, Department of Anaesthesia and Perioperative Medicine, D23 Groote Schuur Hospital, Faculty of Health Sciences, Anzio Rd, Observatory, Cape Town, 7925, South Africa. romy.parker@uct.ac.za.
Groote Schuur Hospital · ZANelson Mandela Academic Hospital · ZABionics Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe previously performed a systematic review and meta-analysis which revealed a Phantom Limb Pain (PLP) prevalence estimate of 64% [95% CI: 60.01-68.1]. The prevalence estimates varied significantly between developed and developing countries. Remarkably, there is limited evidence on the prevalence of PLP and associated risk factors in African populations.

methodsAdults who had undergone limb amputations between January 2018 and October 2022 were recruited from healthcare facilities in the Western and Eastern Cape Provinces. We excluded individuals with auditory or speech impairments that hindered clear communication via telephone. Data on the prevalence and risk factors for PLP were collected telephonically from consenting and eligible participants. The prevalence of PLP was expressed as a percentage with a 95% confidence interval. The associations between PLP and risk factors for PLP were tested using univariate and multivariable logistic regression analyses. The strength of association was calculated using the Odds Ratio where association was confirmed.

resultsThe overall PLP prevalence was 71.73% [95% CI: 65.45-77.46]. Persistent pre-operative pain, residual limb pain, and non-painful phantom limb sensations were identified as risk factors for PLP.

conclusionThis study revealed a high prevalence of PLP. The use of effective treatments targeting pre-amputation pain may yield more effective and targeted pre-amputation care, leading to improved quality of life after amputation.

Indexed as

Phantom LimbCross-Sectional StudiesHumansPrevalenceQuality of LifeRisk FactorsAfricaLimb amputationsPhantom limb painPrevalenceRisk factors

Identifiers

PMID38321380
PMCPMC10845739
OpenAlexW4391573373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.