ArticleNature neuroscience2024
Dopamine transients follow a striatal gradient of reward time horizons.
Article in Nature neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed.
- Article
- Striatal endocannabinoids drive one-shot learning.Nature neuroscience · 2026Article
- The therapeutic potential of COMT inhibition: cognition and beyond.Molecular psychiatry · 2026Review
- Striatal dopamine signals internal states related to behavioral performance over prolonged timescales in monkeys.bioRxiv : the preprint server for biology · 2026Article
- Prediction error correlates in the striosome-dopamine circuit emerge from information gain.Nature communications · 2026Article
- The parafascicular thalamus steers attention to facilitate learning.bioRxiv : the preprint server for biology · 2026Article
- Enhanced reward coding and condition-independent dynamics in optogenetically identified corticostriatal neurons in monkeys.Nature communications · 2026Article
- Mesolimbic Dopaminergic Encoding of Decision Value: Linking Phenotype-Specific Signals to Strategic Adaptation.Neuroscience bulletin · 2026Article
- Article
- Mouse model of atypical DAT deficiency syndrome uncovers dopamine dysfunction associated with parkinsonism and ADHD.The Journal of clinical investigation · 2026Article
- Rapid dopaminergic signatures in movement: Reach vigor reflects reward prediction error and learned expectation.Science advances · 2026Article
- Dopamine Responses in Medial Frontal Cortex Are More Consistent with a Generalized Arousal Signal Than Signed Reward Prediction Errors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Computational modelling identifies key determinants of subregion-specific dopamine dynamics in the striatum.eLife · 2026Article
- Aberrant striatal firing mediates impulsive decision-making in a mouse model of Parkinson's disease.Brain : a journal of neurology · 2026Article
- A brief history of dopamine prediction errors.Frontiers in computational neuroscience · 2026Review
- Timescales of dopamine release in the striatum as a window into hierarchical control.Current opinion in behavioral sciences · 2025Article
- Neurodegenerative Disease Movement Disorders and Dorsal Striatum-Mediated Imbalance of Habitual Motor Sequences.Molecular neurobiology · 2025Review
- Trial-by-trial learning of successor representations in human behavior.bioRxiv : the preprint server for biology · 2025Article
- VTA dopamine neuron activity produces spatially organized value representations.bioRxiv : the preprint server for biology · 2025Article
- Trial-by-trial learning of successor representations in human behavior.PLoS computational biology · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Animals make predictions to guide their behavior and update those predictions through experience. Transient increases in dopamine (DA) are thought to be critical signals for updating predictions. However, it is unclear how this mechanism handles a wide range of behavioral timescales-from seconds or less (for example, if singing a song) to potentially hours or more (for example, if hunting for food). Here we report that DA transients in distinct rat striatal subregions convey prediction errors based on distinct time horizons. DA dynamics systematically accelerated from ventral to dorsomedial to dorsolateral striatum, in the tempo of spontaneous fluctuations, the temporal integration of prior rewards and the discounting of future rewards. This spectrum of timescales for evaluative computations can help achieve efficient learning and adaptive motivation for a broad range of behaviors.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.