Evidence map›Paper›PMID 38321232›Full record

ArticleEJNMMI physics2024

How to obtain the image-derived blood concentration from

Jessica E Wijngaarden, Amina Ahbari, Johanna E E Pouw, Henri N J M Greuter, Idris Bahce, Gerben J C Zwezerijnen, Daniëlle J Vugts, Guus A M S van Dongen, Ronald Boellaard, C Willemien Menke-van der Houven van Oordt and 1 more

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Article in EJNMMI physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jessica E WijngaardenDepartment of Radiology and Nuclear Medicine, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. j.e.wijngaarden@amsterdamumc.nl.ORCID http://orcid.org/0000-0003-1486-6246
Amina AhbariDepartment of Radiology and Nuclear Medicine, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Johanna E E PouwCancer Center Amsterdam, Imaging and Biomarkers, Amsterdam, The Netherlands.
Henri N J M GreuterDepartment of Radiology and Nuclear Medicine, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Idris BahceCancer Center Amsterdam, Imaging and Biomarkers, Amsterdam, The Netherlands.
Gerben J C ZwezerijnenDepartment of Radiology and Nuclear Medicine, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Daniëlle J VugtsDepartment of Radiology and Nuclear Medicine, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Guus A M S van DongenDepartment of Radiology and Nuclear Medicine, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Ronald BoellaardDepartment of Radiology and Nuclear Medicine, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
C Willemien Menke-van der Houven van OordtCancer Center Amsterdam, Imaging and Biomarkers, Amsterdam, The Netherlands.
Marc C HuismanDepartment of Radiology and Nuclear Medicine, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.

Funding

Innovative Medicines Initiative 831514
6 · The paper itself

Abstract

backgroundPET scans using zirconium-89 labelled monoclonal antibodies (

methodsPET imaging and blood sampling of two

resultsOverall, the activity concentration obtained from the IDBC was lower than from the SDBC. When comparing IDBC with SDBC, variability was smallest for the ascending aorta (20.3% and 17.0% for

conclusionsImage-derived blood concentrations should be obtained from delineating the ascending aorta in

Indexed as

89Zr-immuno-PETBlood samplingImage-derived blood concentrationMonoclonal antibodies

Identifiers

PMID38321232
PMCPMC10847076

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.