Evidence map›Paper›PMID 38321106›Full record

ArticleLeukemia2024

LIN28B promotes differentiation of fully transformed AML cells but is dispensable for fetal leukemia suppression.

Yanan Li, Jonny Mendoza-Castrejon, Riddhi M Patel, Emily B Casey, Elisabeth Denby, David Bryder, Jeffrey A Magee

Open access · hybridAbstract readLetter
In one paragraph

Article in Leukemia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Regulation of HSC development and function by Lin28b.Frontiers in cell and developmental biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Yanan LiDivision of Hematology and Oncology, Department of Pediatrics, Washington University School of Medicine, 660 S. Euclid Ave, St. Louis, MO, 63110, USA.ORCID http://orcid.org/0000-0003-4396-0557
Jonny Mendoza-CastrejonDivision of Hematology and Oncology, Department of Pediatrics, Washington University School of Medicine, 660 S. Euclid Ave, St. Louis, MO, 63110, USA.ORCID http://orcid.org/0000-0001-9558-152X
Riddhi M PatelDivision of Hematology and Oncology, Department of Pediatrics, Washington University School of Medicine, 660 S. Euclid Ave, St. Louis, MO, 63110, USA.
Emily B CaseyDivision of Hematology and Oncology, Department of Pediatrics, Washington University School of Medicine, 660 S. Euclid Ave, St. Louis, MO, 63110, USA.
Elisabeth DenbyDivision of Hematology and Oncology, Department of Pediatrics, Washington University School of Medicine, 660 S. Euclid Ave, St. Louis, MO, 63110, USA.
David BryderDivision of Molecular Hematology, Department of Laboratory Medicine, Lund University, 221 84, Lund, Sweden.ORCID http://orcid.org/0000-0002-8761-4237
Jeffrey A MageeDivision of Hematology and Oncology, Department of Pediatrics, Washington University School of Medicine, 660 S. Euclid Ave, St. Louis, MO, 63110, USA. mageej@wustl.edu.ORCID http://orcid.org/0000-0002-0766-4200
Washington University in St. Louis · USLund University · SE

Funding

The role of Kmt2c/MLL3 in hematopoietic stem cell self-renewal, commitment and exhaustionR01HL152180 · NHLBI · WASHINGTON UNIVERSITY · PI Jeffrey Alan Magee · 2020 to 2026
$3.0M
Cross-species development and credentialing of pediatric AML modelsR01CA285272 · NCI · WASHINGTON UNIVERSITY · PI Jeffery M Klco, Jeffrey Alan Magee · 2024 to 2026
$2.0M
TEMPORAL CHANGES IN MECHANISMS OF HSC SELF-RENEWAL AND MYELOID LEUKEMOGENESISR01HL136504 · NHLBI · WASHINGTON UNIVERSITY · PI MAGEE, JEFFREY ALAN · 2017 to 2021
$1.9M
The Role of SKIDA1 in Acute Myeloid Leukemia Initiation and MaintenanceF31CA268923 · NCI · WASHINGTON UNIVERSITY · PI MENDOZA-CASTREJON, JONNY · 2023 to 2024
$69k
NCI NIH HHS F31 CA268923NCI NIH HHS R01 CA285272NHLBI NIH HHS R01 HL136504NHLBI NIH HHS R01 HL152180
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Leukemia, Myeloid, AcuteMicroRNAsCell DifferentiationFetusHumansRNA-Binding ProteinsLIN28B protein, humanMicroRNAsRNA-Binding Proteins

Identifiers

PMID38321106
PMCPMC10912017
OpenAlexW4391560641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.