Evidence map›Paper›PMID 38321028›Full record

ArticleNature communications2024

Shape-recovery of implanted shape-memory devices remotely triggered via image-guided ultrasound heating.

Yang Zhu, Kaicheng Deng, Jianwei Zhou, Chong Lai, Zuwei Ma, Hua Zhang, Jiazhen Pan, Liyin Shen, Matthew D Bucknor, Eugene Ozhinsky and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. A Roadmap to Holographic Focused Ultrasound Approaches for Generating Gradient Thermal Patterns.International journal for numerical methods in biomedical engineering · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yang Zhu *MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, Zhejiang, China. zhuyang@zju.edu.cn.ORCID 0000-0002-7384-607X
Kaicheng Deng *MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, Zhejiang, China.
Jianwei Zhou *School of Electromechanical and Energy Engineering, NingboTech University, Ningbo, Zhejiang, China.
Chong Lai *Department of Urology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Zuwei MaMcGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Hua ZhangCollege of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang, China.
Jiazhen PanCollege of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang, China.
Liyin ShenMOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, Zhejiang, China.
Matthew D BucknorRadiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
Eugene OzhinskyRadiology and Biomedical Imaging, University of California, San Francisco, CA, USA.ORCID 0000-0001-8993-7905
Seungil KimMcGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-4231-3721
Guangjie ChenDepartment of Urology, The Children's Hospital, School of Medicine, National Clinical Research Center for Child Health, Zhejiang University, Hangzhou, Zhejiang, China.
Sang-Ho YeMcGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Yue ZhangSan Francisco Veterans Affairs Medical Center, University of California, San Francisco, CA, USA.
Donghong LiuCollege of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang University, Hangzhou, Zhejiang, China.
Changyou GaoMOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, Zhejiang, China.ORCID 0000-0001-5084-7208
Yonghua XuDepartment of Imaging and Interventional Radiology, Zhongshan-Xuhui Hospital of Fudan University/Shanghai Xuhui Central Hospital, Shanghai, China. howardyonghua@yeah.net.
Huanan WangCollege of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang, China. hnwang@zju.edu.cn.
William R WagnerMcGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA. wagnerwr@upmc.edu.ORCID 0000-0003-0082-8089

Funding

Biodegradable, Thermoresponsive Hydrogels to Treat Ischemic CardiomyopathyR01HL105911 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WAGNER, WILLIAM R · 2011 to 2015
$1.8M
NHLBI NIH HHS R01 HL105911
6 · The paper itself

Abstract

Shape-memory materials hold great potential to impart medical devices with functionalities useful during implantation, locomotion, drug delivery, and removal. However, their clinical translation is limited by a lack of non-invasive and precise methods to trigger and control the shape recovery, especially for devices implanted in deep tissues. In this study, the application of image-guided high-intensity focused ultrasound (HIFU) heating is tested. Magnetic resonance-guided HIFU triggered shape-recovery of a device made of polyurethane urea while monitoring its temperature by magnetic resonance thermometry. Deformation of the polyurethane urea in a live canine bladder (5 cm deep) is achieved with 8 seconds of ultrasound-guided HIFU with millimeter resolution energy focus. Tissue sections show no hyperthermic tissue injury. A conceptual application in ureteral stent shape-recovery reduces removal resistance. In conclusion, image-guided HIFU demonstrates deep energy penetration, safety and speed.

Indexed as

High-Intensity Focused Ultrasound AblationPolyurethanesAnimalsDogsHeatingMagnetic Resonance ImagingUreapolyetherurethane ureaPolyurethanesUrea

Identifiers

PMID38321028
PMCPMC10847440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.