Evidence map›Paper›PMID 38320815›Full record

ArticleESC heart failure2024

Investigating the relationship between FRailty And Quality of LIfe in patients with heart faiLure and CKD (FRAIL study).

Thomas McNally, Ella Tumelty, Isaac Chung, Sabba Hussain, Souradip Mookerjee, Mahrukh Ayesha Ali, Lisa Anderson, Giuseppe Rosano, Debasish Banerjee

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In one paragraph

Article in ESC heart failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thomas McNallySt George's University Hospitals NHS Foundation Trust, London, UK.
Ella TumeltySt George's University Hospitals NHS Foundation Trust, London, UK.
Isaac ChungSt George's University Hospitals NHS Foundation Trust, London, UK.
Sabba HussainSt George's University Hospitals NHS Foundation Trust, London, UK.
Souradip MookerjeeSt George's University Hospitals NHS Foundation Trust, London, UK.
Mahrukh Ayesha AliSt George's University Hospitals NHS Foundation Trust, London, UK.
Lisa AndersonSt George's University Hospitals NHS Foundation Trust, London, UK.
Giuseppe RosanoIRCCS San Raffaele Pisana, Rome, Italy.
Debasish BanerjeeSt George's University Hospitals NHS Foundation Trust, London, UK.

Funding

St George's University Academic Training (GAT)
6 · The paper itself

Abstract

aimsPatients with chronic kidney disease (CKD) or heart failure (HF) are disproportionally affected by frailty, an independent predictor of morbidity. The prevalence of frailty and its impact on quality of life (QoL) in a unique population of patients with both CKD and HF (CKD-HF) is unclear. The aim of this study was to investigate the association between frailty and QoL in patients with CKD-HF. METHODS AND

resultsPatients were identified from a tertiary care cardiorenal clinic. Eligible patients had CKD-HF with a stable estimated glomerular filtration rate of <60 mL/min/1.73

conclusionsA large proportion of CKD-HF patients are frail, regardless of disease severity, and more susceptible to significantly poorer QoL across physical and social domains. Improving QoL is the priority of patients across both frail and non-frail cohorts, further emphasizing the need for prompt recognition of frailty as well as possible intervention and prevention.

Indexed as

FrailtyGlomerular Filtration RateHeart FailureQuality of LifeRenal Insufficiency, ChronicAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedPrevalenceRetrospective StudiesSurveys and QuestionnairesChronic kidney failureFrailtyHeart failureObservationalQuality of life

Identifiers

PMID38320815
PMCPMC11098643

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.