Evidence map›Paper›PMID 38320533›Full record

ArticleNEJM evidence2023

Prior Ground: Selection of Prior Distributions When Analyzing Clinical Trial Data Using Bayesian Methods.

Juned Siddique, Zeynab Aghabazaz

Abstract readEditorialComment
In one paragraph

Article in NEJM evidence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Juned SiddiqueDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago.
Zeynab AghabazazDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago.

Funding

Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI MILDA Renne SAUNDERS · 2011 to 2026
$10.0M
Combining longitudinal cohort studies to examine cardiovascular risk factor trajectories across the adult lifespan and their association with diseaseR01HL158963 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DANIELS, MICHAEL J, SIDDIQUE, JUNED · 2021 to 2024
$2.3M
NHLBI NIH HHS R01 HL158963NIDDK NIH HHS P30 DK092949
6 · The paper itself

Abstract

Increasingly, investigators are choosing to use Bayesian methods for the analysis of clinical trial data. Unlike classical statistical methods that treat model parameter values (such as treatment effects) as fixed, Bayesian methods view parameters as following a probability distribution. As we have written previously,

Indexed as

Bayes TheoremHumansProbability

Identifiers

PMID38320533
PMCPMC11197078

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.