Evidence map›Paper›PMID 38319951›Full record

ArticlePloS one2024

Factors associated with anxiety during the first two years of the COVID-19 pandemic in the United States: An analysis of the COVID-19 Citizen Science study.

Aaron E Cozen, Thomas Carton, Rita Hamad, John Kornak, Madelaine Faulkner Modrow, Noah D Peyser, Soo Park, Jaime H Orozco, Matthew Brandner, Emily C O'Brien and 7 more

Registry-linked trialAbstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05548803 (Comparing Patient-reported Impact of COVID-19 Shelter-in-place Policies and Access to Containment and Mitigation Strategies, Overall and in Vulnerable Populations), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05548803 completednot on this map

Comparing Patient-reported Impact of COVID-19 Shelter-in-place Policies and Access to Containment and Mitigation Strategies, Overall and in Vulnerable Populations

TypeobservationalSponsorUniversity of California, San FranciscoRan2020 to 2024Enrolled52,351ConditionsCovid19
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Aaron E CozenDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, United States of America.ORCID 0000-0003-2409-0023
Thomas CartonLouisiana Public Health Institute, New Orleans, LA, United States of America.
Rita HamadDept of Social and Behavioral Sciences, Harvard School of Public Health, Boston, MA, United States of America.
John KornakDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, United States of America.
Madelaine Faulkner ModrowDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, United States of America.
Noah D PeyserDivision of Cardiology, University of California, San Francisco, San Francisco, CA, United States of America.ORCID 0000-0003-4529-8325
Soo ParkDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, United States of America.ORCID 0009-0009-3866-2919
Jaime H OrozcoDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, United States of America.ORCID 0009-0008-0813-1175
Matthew BrandnerDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, United States of America.
Emily C O'BrienDuke Clinical Research Institute, Durham, NC, United States of America.
Djeneba Audrey DjiboCVS Health Clinical Trial Services, Blue Bell, PA, United States of America.ORCID 0000-0003-3378-0691
Cheryl N McMahill-WalravenCVS Health Clinical Trial Services, Blue Bell, PA, United States of America.ORCID 0000-0002-3765-6527
Carmen R IsasiDepartment of Epidemiology, Albert Einstein College of Medicine, The Bronx, NY, United States of America.
Alexis L BeattyDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, United States of America.
Jeffrey E OlginDivision of Cardiology, University of California, San Francisco, San Francisco, CA, United States of America.ORCID 0000-0003-1684-9327
Gregory M MarcusDivision of Cardiology, University of California, San Francisco, San Francisco, CA, United States of America.
Mark J PletcherDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, United States of America.

Funding

The Health ePeople Resource for Mobilized ResearchU2CEB021881 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARCUS, GREGORY M, OLGIN, JEFFREY E · 2015 to 2020
$10.3M
MHC Variation in Host Response to SARS-CoV2 and COVID-19 OutcomesR01AI159260 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HOLLENBACH, JILL ALLISON · 2021 to 2025
$4.0M
Bill and Melinda Gates INV-017206NIAID NIH HHS R01 AI159260NIH HHS 3U2CEB021881-05S1
6 · The paper itself

Abstract

COVID-19 increased the prevalence of clinically significant anxiety in the United States. To investigate contributing factors we analyzed anxiety, reported online via monthly Generalized Anxiety Disorders-7 (GAD-7) surveys between April 2020 and May 2022, in association with self-reported worry about the health effects of COVID-19, economic difficulty, personal COVID-19 experience, and subjective social status. 333,292 anxiety surveys from 50,172 participants (82% non-Hispanic white; 73% female; median age 55, IQR 42-66) showed high levels of anxiety, especially early in the pandemic. Anxiety scores showed strong independent associations with worry about the health effects of COVID-19 for oneself or family members (GAD-7 score +3.28 for highest vs. lowest category; 95% confidence interval: 3.24, 3.33; p<0.0001 for trend) and with difficulty paying for basic living expenses (+2.06; 1.97, 2.15, p<0.0001) in multivariable regression models after adjusting for demographic characteristics, COVID-19 case rates and death rates, and personal COVID-19 experience. High levels of COVID-19 health worry and economic stress were each more common among participants reporting lower subjective social status, and median anxiety scores for those experiencing both were in the range considered indicative of moderate to severe clinical anxiety disorders. In summary, health worry and economic difficulty both contributed to high rates of anxiety during the first two years of the COVID-19 pandemic in the US, especially in disadvantaged socioeconomic groups. Programs to address both health concerns and economic insecurity in vulnerable populations could help mitigate pandemic impacts on anxiety and mental health.

Indexed as

Citizen ScienceCOVID-19AnxietyAnxiety DisordersDepressionFemaleHumansMaleMiddle AgedPandemicsSARS-CoV-2United States

Identifiers

PMID38319951
PMCPMC10846720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.