ReviewLa Radiologia medica2024
Imaging biomarkers in cardiac CT: moving beyond simple coronary anatomical assessment.
Review in La Radiologia medica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Precision or Paradox? AI-Driven Adiposity Imaging in Women With Overweight and Obesity: A Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Pathophysiology, diagnosis and intervention strategies of nocturnal hypertension.Journal of human hypertension · 2026Review
- Cardiac CT in the Era of Precision Cardiology: From Calcium Scoring to Comprehensive Risk Profiling.Journal of clinical medicine · 2026Review
- Unraveling Atherosclerosis through Multi-omics: Systematic Insights into the Unique Applications and Clinical Perspectives.Current atherosclerosis reports · 2026Review
- Unsupervised risk factor identification across cancer types and data modalities via explainable artificial intelligence.NPJ digital medicine · 2026Article
- Does adding a delayed phase to cardiac computed tomography for coronary artery evaluation have prognostic value?European heart journal. Cardiovascular Imaging · 2026Article
- Pericoronary Adipose Tissue Radiomic Features and Quantitative Plaque Analysis in Coronary Artery Disease: Insights from Coronary Computed Tomography Angiography.Diagnostics (Basel, Switzerland) · 2026Article
- Mediation of stenosis-induced ischemia by proximal peri-coronary adipose tissue: A cross-sectional study.Medicine · 2026Article
- Feasibility of Artificial Intelligence Models for Longitudinal CT Analysis of Epicardial Adipose Tissue After Immunotherapy.Diagnostics (Basel, Switzerland) · 2026Article
- Evaluation of myocardial microcirculation changes in rats from different altitudes based on CT myocardial perfusion imaging.Biochemistry and biophysics reports · 2026Article
- Advanced myocardial characterization and function with cardiac CT.The international journal of cardiovascular imaging · 2026Review
- Emerging quantitative CCTA imaging biomarkers for cardiovascular risk stratification: a narrative review.Frontiers in cardiovascular medicine · 2026Review
- Preliminary exploration of the value of pericoronary adipose tissue radiomics in identifying high-risk patients with chronic coronary syndrome: a retrospective Chinese cohort study.Frontiers in medicine · 2026Article
- Accuracy of photon-counting detector CT-based iodine maps for myocardial late enhancement detection.European radiology · 2025Article
- From Heart to Abdominal Aorta: Integrating Multi-Modal Cardiac Imaging Derived Haemodynamic Biomarkers for Abdominal Aortic Aneurysm Risk Stratification, Surveillance, Pre-Operative Assessment and Therapeutic Decision-Making.Diagnostics (Basel, Switzerland) · 2025Review
- Beyond Traditional Risk Factors: Integrating Epicardial Adipose Tissue into the Comorbidity Landscape of HFpEF.Journal of clinical medicine · 2025Review
- Computed Tomography Advancements in Plaque Analysis: From Histology to Comprehensive Plaque Burden Assessment.Echocardiography (Mount Kisco, N.Y.) · 2025Review
- Epicardial Adipose Tissue: A Multimodal Imaging Diagnostic Perspective.Medicina (Kaunas, Lithuania) · 2025Review
- State of the art of CT myocardial perfusion.La Radiologia medica · 2025Review
- Prognosis prediction in type B aortic intramural hematoma patients using a combined model based on aortic computed tomography angiography radiomics.Quantitative imaging in medicine and surgery · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiac computed tomography angiography (CCTA) is considered the standard non-invasive tool to rule-out obstructive coronary artery disease (CAD). Moreover, several imaging biomarkers have been developed on cardiac-CT imaging to assess global CAD severity and atherosclerotic burden, including coronary calcium scoring, the segment involvement score, segment stenosis score and the Leaman-score. Myocardial perfusion imaging enables the diagnosis of myocardial ischemia and microvascular damage, and the CT-based fractional flow reserve quantification allows to evaluate non-invasively hemodynamic impact of the coronary stenosis. The texture and density of the epicardial and perivascular adipose tissue, the hypodense plaque burden, the radiomic phenotyping of coronary plaques or the fat radiomic profile are novel CT imaging features emerging as biomarkers of inflammation and plaque instability, which may implement the risk stratification strategies. The ability to perform myocardial tissue characterization by extracellular volume fraction and radiomic features appears promising in predicting arrhythmogenic risk and cardiovascular events. New imaging biomarkers are expanding the potential of cardiac CT for phenotyping the individual profile of CAD involvement and opening new frontiers for the practice of more personalized medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.