Evidence map›Paper›PMID 38319453›Full record

ReviewCancer metastasis reviews2024

Clusterin: a marker and mediator of chemoresistance in colorectal cancer.

Sara Hlavca, Wing Hei Chan, Rebekah M Engel, Helen E Abud

Open access · hybridAbstract readReview
In one paragraph

Review in Cancer metastasis reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Ghrelin Induces CluInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sara Hlavca *Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, 3800, Australia.
Wing Hei Chan *Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, 3800, Australia.
Rebekah M EngelDepartment of Anatomy and Developmental Biology, Monash University, Clayton, VIC, 3800, Australia.
Helen E AbudDepartment of Anatomy and Developmental Biology, Monash University, Clayton, VIC, 3800, Australia. helen.abud@monash.edu.
Australian Regenerative Medicine Institute · AUMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intra-tumoural heterogeneity and cancer cell plasticity in colorectal cancer (CRC) have been key challenges to effective treatment for patients. It has been suggested that a subpopulation of LGR5-expressing cancer stem cells (CSCs) is responsible for driving tumour relapse and therapy resistance in CRC. However, studies have revealed that the LGR5

Indexed as

Colorectal NeoplasmsDrug Resistance, NeoplasmAnimalsClusterinHumansNeoplastic Stem CellsCLU protein, humanClusterinChemotherapyCLUColorectal cancerRegenerative stem cellsTumour relapse

Identifiers

PMID38319453
PMCPMC11015998
OpenAlexW4391575034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.