Evidence map›Paper›PMID 38319152›Full record

ArticleeLife2024

Inhibition of

Claire C Chen, Joseph Han, Carlene A Chinn, Jacob S Rounds, Xiang Li, Mehran Nikan, Marie Myszka, Liqi Tong, Luiz F M Passalacqua, Timothy Bredy and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Role of CPEBs in Learning and Memory.Journal of neurochemistry · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Claire C ChenDepartment of Pharmaceutical Sciences, University of California, Irvine, Irvine, United States.ORCID https://orcid.org/0000-0003-2490-2909
Joseph HanDepartment of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, United States.
Carlene A ChinnDepartment of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, United States.
Jacob S RoundsDepartment of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, United States.
Xiang LiDepartment of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, United States.
Mehran NikanIonis Pharmaceuticals, Carlsbad, United States.
Marie MyszkaDepartment of Chemistry, University of California, Irvine, Irvine, United States.
Liqi TongInstitute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, United States.
Luiz F M PassalacquaDepartment of Pharmaceutical Sciences, University of California, Irvine, Irvine, United States.ORCID https://orcid.org/0000-0002-5490-2427
Timothy BredyDepartment of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, United States.ORCID https://orcid.org/0000-0003-3280-126X
Marcelo A WoodDepartment of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, United States.
Andrej LuptakDepartment of Pharmaceutical Sciences, University of California, Irvine, Irvine, United States.ORCID https://orcid.org/0000-0002-0632-5442
University of California, Irvine · USThe University of Queensland · AUIonis Pharmaceuticals (United States) · US

Funding

Epigenetic suppression of histone methylation reverses age and AD-related cognitive declineRF1AG057558 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI WOOD, MARCELO ANDRES · 2018 to 2018
$3.8M
Exercise-induced epigenetic mechanisms underlying neuronal plasticity and cognitionR01AG051807 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI COTMAN, CARL WAYNE, WOOD, MARCELO ANDRES · 2016 to 2020
$3.1M
Role of UHRF1 in osteosarcoma metastasisR01CA229696 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI BENAVENTE, CLAUDIA ANDREA · 2019 to 2023
$2.4M
NCI NIH HHS R01 CA229696NIA NIH HHS R01 AG051807NIA NIH HHS RF1 AG057558NIH HHS R01AG051807NIH HHS R01CA229696NIH HHS RF1AG057558
6 · The paper itself

Abstract

A self-cleaving ribozyme that maps to an intron of the cytoplasmic polyadenylation element-binding protein 3 (

Indexed as

RNA, CatalyticAnimalsHumansMemory, Long-TermMiceNeuronsPolyadenylationRNA-Binding ProteinsRNA, MessengerCPEB3 protein, humanCpeb3 protein, mouseRNA-Binding ProteinsRNA, CatalyticRNA, MessengerchromosomesCPEB3gene expressionmouseneuroplasticityneuroscienceribozyme

Identifiers

PMID38319152
PMCPMC10919898
OpenAlexW4391565015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.