Evidence map›Paper›PMID 38318664›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2024

Recapitulation of human pathophysiology and identification of forensic biomarkers in a translational model of chlorine inhalation injury.

Satyanarayana Achanta, Michael A Gentile, Carolyn J Albert, Kevin A Schulte, Brooke G Pantazides, Brian S Crow, Jennifer Quiñones-González, Jonas W Perez, David A Ford, Rakesh P Patel and 3 more

Open access · hybridAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The long road to Ithaca: a physiologist's journey.American journal of physiology. Cell physiology · 2025
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Satyanarayana AchantaDepartment of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, United States.ORCID 0000-0001-7121-5445
Michael A GentileDepartment of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, United States.
Carolyn J AlbertDepartment of Biochemistry and Molecular Biology, Saint Louis University, St. Louis, Missouri, United States.
Kevin A SchulteDepartment of Biochemistry and Molecular Biology, Saint Louis University, St. Louis, Missouri, United States.
Brooke G PantazidesDivision of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States.
Brian S CrowDivision of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States.
Jennifer Quiñones-GonzálezDivision of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States.
Jonas W PerezDivision of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States.
David A FordDepartment of Biochemistry and Molecular Biology, Saint Louis University, St. Louis, Missouri, United States.
Rakesh P PatelCenter for Free Radical Biology and Lung Injury and Repair Center, The University of Alabama at Birmingham, Birmingham, Alabama, United States.ORCID 0000-0002-1526-4303
Thomas A BlakeDivision of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States.ORCID 0000-0001-8536-9998
Michael D GunnDepartment of Medicine, Duke University School of Medicine, Durham, North Carolina, United States.
Sven E JordtDepartment of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, United States.
Centers for Disease Control and Prevention · USDuke University · USSaint Louis University · USUniversity of Alabama at Birmingham · US

Funding

Chlorinated lipids in sepsisR01GM115553 · NIGMS · SAINT LOUIS UNIVERSITY · PI FORD, DAVID A., MCHOWAT, JANE · 2015 to 2021
$3.0M
Advanced TRPA1 Inhibitor for the Treatment of Chlorine Inhalation InjuryU01ES030672 · NIEHS · DUKE UNIVERSITY · PI ACHANTA, SATYANARAYANA, JORDT, SVEN-ERIC · 2019 to 2021
$2.3M
Pulmonary cell fate and lung repair in rodent and porcine models of chlorine and phosgene inhalation injuriesR01ES034387 · NIEHS · DUKE UNIVERSITY · PI ACHANTA, SATYANARAYANA, JORDT, SVEN-ERIC · 2022 to 2024
$1.4M
Specialized pro-resolving mediators as potential medical countermeasures in a pig model of chlorine gas-induced acute lung injuryR21ES030331 · NIEHS · DUKE UNIVERSITY · PI ACHANTA, SATYANARAYANA, JORDT, SVEN-ERIC · 2020 to 2021
$443k
Inhibition of soluble epoxide hydrolase protects against phosgene-induced lung injuriesR21ES033020 · NIEHS · DUKE UNIVERSITY · PI ACHANTA, SATYANARAYANA · 2021 to 2022
$443k
NIEHS NIH HHS R01 ES034387NIEHS NIH HHS R21 ES030331NIEHS NIH HHS R21 ES033020NIEHS NIH HHS U01 ES030672NIGMS NIH HHS R01 GM115553
6 · The paper itself

Abstract

Chlorine gas (Cl

Indexed as

Acute Lung InjuryChlorineAnimalsBiomarkersBronchoalveolar Lavage FluidFatty AcidsHumansLungSwineBiomarkersChlorineFatty Acidsacute lung injurychlorinemedical countermeasurepig translational modelUS FDA animal rule (21 CFR 314.600)

Identifiers

PMID38318664
PMCPMC11281795
OpenAlexW4391574465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.