Evidence map›Paper›PMID 38318576›Full record

ReviewCureus2024

Unlocking the Potential of Cellular Guidance in Endodontics: Advancing the Process of Pulp Regeneration and Beyond.

Tariq M Alharbi, Arwa M Thabet, Shaqran H Alabbadi, Majed Y Alhazmi, Hanan F Khan, Manar A AlRasheed, Noor A Al-Twalbeh, Abdulmalik S Alsuhaim, Nadeen S Alqahtani

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Cell homing within endodontic hydrogels: A scoping review.The Japanese dental science review · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tariq M AlharbiEndodontics, King Fahad General Hospital, Medina, SAU.
Arwa M ThabetDentistry, Ministry of Health, Riyadh, SAU.
Shaqran H AlabbadiDentistry, Umm Al-Qura University, Makkah, SAU.
Majed Y AlhazmiDentistry, Jazan University, Jazan, SAU.
Hanan F KhanDentistry, Dar Al Uloom University, Riyadh, SAU.
Manar A AlRasheedDentistry, Dar Al Uloom University, Riyadh, SAU.
Noor A Al-TwalbehDentistry, Prince Mohammed Bin Abdulaziz Hospital, Madinah, SAU.
Abdulmalik S AlsuhaimDentistry, Ministry of Health, Riyadh, SAU.
Nadeen S AlqahtaniDentistry, Ministry of Health, Riyadh, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regenerative endodontics represents a paradigm shift in dental therapy, with the potential to not only restore damaged dental tissues but also to preserve the vitality of teeth. At the heart of this innovative approach is cell homing, a technique that harnesses the body's own healing mechanisms by recruiting endogenous stem cells to the site of dental injury for effective tissue regeneration. This review delves into the intricate processes of cell homing in the context of regenerative endodontics, particularly focusing on its application in immature teeth with open apices. It examines the role of bioactive molecules, scaffolds, and growth factors in orchestrating cell migration and differentiation within the root canal space. In addition, the review addresses the current limitations in clinical practice, such as the challenges in completely regenerating the pulp-dentin complex and the unpredictability in long-term outcomes. It also explores future possibilities, including the potential for more refined and effective regenerative strategies. By providing a comprehensive overview of the current state of cell homing in regenerative endodontics, this article aims to contribute to the ongoing development of advanced therapeutic techniques that could revolutionize endodontic treatment and improve patient care.

Indexed as

endodontic managementendodontic regenerationendodontic treatmentendodontic treatment outcomesstem cell

Identifiers

PMID38318576
PMCPMC10839349

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.