Evidence map›Paper›PMID 38318546›Full record

ArticleCureus2024

Evaluation of Antibacterial, Antioxidant, Anti-inflammatory and Anticancer Efficacy of Titanium-Doped Graphene Oxide Nanoparticles.

S Vishaka, S Nehal Safiya, M Binigha, Durai Singh Carmelin, P Geetha Sravanthy, Ramanathan Snega, Muthuvel Surya, Muthupandian Saravanan

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

S VishakaDepartment of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, IND.
S Nehal SafiyaDepartment of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, IND.
M BinighaDepartment of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, IND.
Durai Singh CarmelinDepartment of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, IND.
P Geetha SravanthyDepartment of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, IND.
Ramanathan SnegaDepartment of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, IND.
Muthuvel SuryaDepartment of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, IND.
Muthupandian SaravananDepartment of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe current development of nanoparticles (NPs) with significant antibacterial properties, low cost and low toxicity has made it possible to develop novel techniques for treatments in the medical field. The titanium metal oxide, when combined with a carbonaceous material like graphene, which has excellent absorbing capacity, is efficient in loading drugs and thus helps in drug delivery and also in biomedical applications like anticancer, anti-inflammatory, antioxidant, and antibacterial activities. MATERIALS AND

methodsTitanium-doped graphene oxide nanoparticles (Ti/GO-NPs) were processed by the one-pot synthesis method; further characterization was performed by using UV-visible spectroscopy, Fourier transform-infrared spectroscopy (FT-IR), field emission electron microscopy (FE-SEM), and energy-dispersive X-ray spectroscopy (EDX) analysis and biomedical applications like anticancer, anti-inflammatory, antioxidant and antibacterial activities.

resultsThe synthesized end product of Ti/GO-NPs showed a creamy white appearance. Subsequent characterization studies of UV-Vis spectroscopy revealed a peak level of 373 nm at 24 hours and 404 nm after 48 hours. FT-IR analysis exhibited a broad absorption band within the range of 1000-3500 cm

conclusionThe characterization and biomedical application conclude that a combination of Ti/GO-NPs will be efficient in drug delivery. The study showed moderate antibacterial activity and significant antioxidant, anti-inflammatory and anticancer activities. Considering their physiochemical properties, absorption capacity and mechanism of drug delivery, Ti/GO-NPs can be incorporated into various applications in the medical field.

Indexed as

antibacterial activityanticanceranti-inflammatoryantioxidanttitanium/graphene nanoparticles

Identifiers

PMID38318546
PMCPMC10840046

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.