Evidence map›Paper›PMID 38318363›Full record

ArticleiScience2024

NG2 glia reprogramming induces robust axonal regeneration after spinal cord injury.

Wenjiao Tai, Xiaolong Du, Chen Chen, Xiao-Ming Xu, Chun-Li Zhang, Wei Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. iScience · 2026
    Article
  4. Article
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  6. Review
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Wenjiao TaiDepartment of Molecular Biology and Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Xiaolong DuDepartment of Neurological Surgery, Spinal Cord and Brain Injury Research Group, Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Chen ChenDepartment of Neurological Surgery, Spinal Cord and Brain Injury Research Group, Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Xiao-Ming XuDepartment of Neurological Surgery, Spinal Cord and Brain Injury Research Group, Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Chun-Li ZhangDepartment of Molecular Biology and Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Wei WuDepartment of Neurological Surgery, Spinal Cord and Brain Injury Research Group, Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Neurological Surgery · USThe University of Texas Southwestern Medical Center · US

Funding

Reprogramming reactive glial cells into functional new neurons after SCIR01NS111776 · NINDS · INDIANA UNIVERSITY INDIANAPOLIS · PI WU, WEI, ZHANG, CHUN-LI · 2020 to 2024
$2.4M
Induced Adult Neurogenesis for Parkinson's DiseaseR01NS092616 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI ZHANG, CHUN-LI · 2016 to 2020
$2.4M
In Vivo Reprogramming of NG2 Glia for NeurogenesisR01NS117065 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI ZHANG, CHUN-LI · 2020 to 2024
$2.1M
Modulation of lumbar motor circuitry after an above-level SCI and NT-3 gene therapyR01NS103481 · NINDS · INDIANA UNIVERSITY INDIANAPOLIS · PI SMITH, GEORGE M, WU, WEI · 2017 to 2021
$1.9M
Chemical Reprogramming of Traumatic Brain InjuryR01NS099073 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI ZHANG, CHUN-LI · 2017 to 2021
$1.8M
In Vivo Reprogramming of Glial Fate for Spinal Cord RepairR01NS088095 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI ZHANG, CHUN-LI · 2014 to 2018
$1.7M
NINDS NIH HHS R01 NS088095NINDS NIH HHS R01 NS092616NINDS NIH HHS R01 NS099073NINDS NIH HHS R01 NS103481NINDS NIH HHS R01 NS111776NINDS NIH HHS R01 NS117065
6 · The paper itself

Abstract

Spinal cord injury (SCI) often leads to neuronal loss, axonal degeneration, and behavioral dysfunction. We recently show that

Indexed as

Cell biologyMolecular biologyNeuroscience

Identifiers

PMID38318363
PMCPMC10839253
OpenAlexW4391021744

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.