ReviewFrontiers in neurology2023
Techniques and graft materials for repairing peripheral nerve defects.
Review in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06977607 (Comparative Study Between Platelet- Rich Fibrin Versus Nano-Fat in Improving Facial Nerve Regeneration After Traumatic Injury), which is not on this map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Study Between Platelet- Rich Fibrin Versus Nano-Fat in Improving Facial Nerve Regeneration After Traumatic Injury
Who cites it
14 citing papers in PubMed.
- Biocompatibility and antibacterial properties of ordered PLA fiber membranes fabricated via electrospinning technology.iScience · 2026Article
- Artificial intelligence and peripheral neuropathies: Strategies for the development, application, and repair of regenerative biomaterials.Neural regeneration research · 2026Article
- Synergistic integration of flexible bioelectroactive nanofibrous conduits and electrical stimulation for accelerated peripheral nerve regeneration.Materials today. Bio · 2026Article
- Silk-Derived 3D-Bioprinted Scaffolds for Neural Repair and Nerve Regeneration: A Comprehensive Review.Life (Basel, Switzerland) · 2026Review
- Localized Tacrolimus Delivery for Peripheral Nerve Regeneration: Molecular Mechanisms, Biomaterial Platforms, and Translational Strategies.International journal of molecular sciences · 2026Review
- Where Do We Stand for Nerve Regeneration and Functional Recovery After Vascularized Composite Allotransplantation?Microsurgery · 2026Review
- Comparative analysis of Antigliotic Guiding Regenerative Gel (AGRG - LDP-916) for peripheral nerve reconstruction: Evidence from prospective randomized controlled studies.Brain & spine · 2026Review
- Optimizing Peripheral Nerve Regeneration: Surgical Techniques, Biomolecular and Regenerative Strategies-A Narrative Review.International journal of molecular sciences · 2025Review
- Chitosan-Based Materials for Peripheral Nerve Repair-New Pre-Clinical Data on Degradation Behavior at the Nerve Repair Site and Critical Opinion on Their Translational Impact.International journal of molecular sciences · 2025Article
- Peripheral nerve regeneration using a biodegradable conduit from açaí (Euterpe oleracea): a bio-based alternative to autografts.Acta cirurgica brasileira · 2025Article
- The ROX@PDA@PCL vascularized bionic nerve conduit facilitates the restoration of nerve defects.Frontiers in neurology · 2025Article
- Article
- Single-cell profiling of cellular changes in the somatic peripheral nerves following nerve injury.Frontiers in pharmacology · 2024Review
- Commentary: Techniques and graft materials for repairing peripheral nerve defects.Frontiers in neurology · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Peripheral nerve defects refer to damage or destruction occurring in the peripheral nervous system, typically affecting the limbs and face. The current primary approaches to address peripheral nerve defects involve the utilization of autologous nerve transplants or the transplantation of artificial material. Nevertheless, these methods possess certain limitations, such as inadequate availability of donor nerve or unsatisfactory regenerative outcomes post-transplantation. Biomaterials have been extensively studied as an alternative approach to promote the repair of peripheral neve defects. These biomaterials include both natural and synthetic materials. Natural materials consist of collagen, chitosan, and silk, while synthetic materials consist of polyurethane, polylactic acid, and polycaprolactone. Recently, several new neural repair technologies have also been developed, such as nerve regeneration bridging technology, electrical stimulation technology, and stem cell therapy technology. Overall, biomaterials and new neural repair technologies provide new methods and opportunities for repairing peripheral nerve defects. However, these methods still require further research and development to enhance their effectiveness and feasibility.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.