Evidence map›Paper›PMID 38318096›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2024

Biofilm-Inhibitory Activity of Wild Mushroom Extracts against Pathogenic Bacteria.

Gebreselema Gebreyohannes, Desta Berhe Sbhatu, Andrew Kimang'a Nyerere, Abrha Gebreselema Gebrehiwot

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gebreselema GebreyohannesDepartment of Biological and Chemical Engineering, Mekelle Institute of Technology, Mekelle University, Mekele, Ethiopia.ORCID https://orcid.org/0000-0003-2697-4818
Desta Berhe SbhatuDepartment of Biological and Chemical Engineering, Mekelle Institute of Technology, Mekelle University, Mekele, Ethiopia.ORCID https://orcid.org/0000-0003-3602-1578
Andrew Kimang'a NyerereDepartment of Medical Microbiology, College of Health Sciences, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.ORCID https://orcid.org/0000-0002-3423-4484
Abrha Gebreselema GebrehiwotDepartment of Medical Biochemistry, College of Health Sciences, Mekelle University, Mekele, Ethiopia.ORCID https://orcid.org/0000-0003-1222-5584

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to investigate the bacterial biofilm-inhibitory effect of mushroom extracts. Methods: Mushrooms were collected from Arabuko-Sokoke and Kakamega forests and identified using morphological and molecular approaches. Results: Chloroform, 70% ethanol, and hot water extracts of Conclusions: Being the first study of its kind to be conducted in Kenya, it added a novel concept to the body of knowledge already known about medical biotechnology research. It offers a fresh understanding of the various varieties of mushrooms found in Kenya, their potential biological function in the production of drugs, particularly those that combat drug resistance, and perhaps even a peek at their bioactive elements. Wild mushrooms, a hidden gem, might help to reopen the pipeline of new antibiotics that have been on the decline. However, further research is required to determine the potential mechanism(s) of action of the extracts that are in charge of the apparent antibiofilm activity.

Identifiers

PMID38318096
PMCPMC10843873

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.