Evidence map›Paper›PMID 38317750›Full record

ArticleTranslational gastroenterology and hepatology2024

TMEM43 promotes the development of hepatocellular carcinoma by activating VDAC1 through USP7 deubiquitination.

Nannan Zhang, Feiran Wang, Xiaobing Yang, Quhui Wang, Renan Chang, Lirong Zhu, Mark A Feitelson, Zhong Chen

Abstract read
In one paragraph

Article in Translational gastroenterology and hepatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Deubiquitylating Enzymes in Hepatocellular Carcinoma.International journal of biological sciences · 2025
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nannan Zhang *Department of General Surgery, Affiliated Hospital of Nantong University, Medical College of Nantong University, Nantong, China.
Feiran Wang *Department of General Surgery, Affiliated Hospital of Nantong University, Medical College of Nantong University, Nantong, China.
Xiaobing Yang *Department of General Surgery, Huai'an Hospital of Huai'an City, Huai'an, China.
Quhui WangDepartment of General Surgery, Affiliated Hospital of Nantong University, Medical College of Nantong University, Nantong, China.
Renan ChangDepartment of General Surgery, Affiliated Hospital of Nantong University, Medical College of Nantong University, Nantong, China.
Lirong ZhuDepartment of General Surgery, Affiliated Hospital of Nantong University, Medical College of Nantong University, Nantong, China.
Mark A FeitelsonDepartment of Biology, College of Science and Technology, Temple University, Philadelphia, PA, USA.
Zhong ChenDepartment of General Surgery, Affiliated Hospital of Nantong University, Medical College of Nantong University, Nantong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Transmembrane protein 43 ( Methods: We utilized the RNA sequencing (RNA-seq) and The Cancer Genome Atlas (TGCA) databases to explore and identify genes that may play an important role in the occurrence and development of hepatocellular carcinoma (HCC), such as Results: In this study, we utilized the RNA-seq and TGCA databases to mine data and found that Conclusions: Our study demonstrated that USP7 participates in the growth of HCC tumors through

Indexed as

hepatocellular carcinoma (HCC)metastasisTransmembrane protein 43 (TMEM43)voltage-dependent anion channel 1 (VDAC1)

Identifiers

PMID38317750
PMCPMC10838614

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.